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562 Results for "

raw

" in MedChemExpress (MCE) Product Catalog:

Products (562)

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165

JSH-23

165 Publications Verification

Cat. No.: HY-13982

CAS No.: 749886-87-1

Purity: 99.30%

Target:

NF-κB

Research Areas:

Metabolic Disease Inflammation/Immunology Cancer

JSH-23 is an NF-κB inhibitor which inhibits NF-κB transcriptional activity with an IC₅₀ of 7.1 μM in lipopolysaccharide (LPS)-stimulated macrophages RAW 264.7. JSH-23 inhibits nuclear translocation of NF-κB p65 without affecting IκBα degradation .

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ML115

8 Cited Publications

Cat. No.: HY-111152

CAS No.: 912798-42-6

Purity: 99.89%

Target:

STAT

Research Areas:

Cancer

ML115, a molecular probe of the signal transducer, is a selective STAT3 agonist, with an EC₅₀ of 2 nM. ML115 increases the expression of BCL3, a known STAT3-dependent oncogene. ML115 is inactive against the related STAT1, STAT5 and NF-κB anti-targets. ML115 counteracts the effects of Ginsenoside Rc (HY-N0042) on cell viability and inflammatory responses in LPS (HY-D1056)-stimulated H9c2 and RAW264.7 cells, while altering oxidative stress markers. ML115 can be used for the study of breast and prostate cancers .

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Urea

7 Cited Publications

Cat. No.: HY-Y0271

CAS No.: 57-13-6

Synonyms: Carbonyl diamide

Category:

Natural Products Microorganisms Endogenous metabolite Disease Research Fields Biological Pesticide Research Cancer Agricultural Research

Target:

Environmental Pollutants Apoptosis Endogenous Metabolite Carbonic Anhydrase ERK

Urea is a powerful protein denaturant via both direct and indirect mechanisms . A potent emollient and keratolytic agent . Used as a diuretic agent. Blood urea nitrogen (BUN) has been utilized to evaluate renal function . Widely used in fertilizers as a source of nitrogen and is an important raw material for the chemical industry.

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Endotoxin Detection Kit (Recombinant Factor C)

5 Cited Publications

Cat. No.: HY-K1099

MCE Endotoxin Detection Kit (Recombinant Factor C) is suitable for the detection of endotoxins in therapeutic injectable drugs for human use (such as chemical drugs, antibiotics, and biologics), as well as in medical devices including dialysis fluids and implantable devices. It can be applied throughout raw material screening, process development, manufacturing, and commercialization stages.