1682 Results for "

reactive

" in MedChemExpress (MCE) Product Catalog:
Products (1682)

1682 Results for "reactive" in MCE Product Catalog:

935
Erastin
Erastin
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935 Publications Verification
Cat. No.: HY-15763
CAS No.: 571203-78-6
Purity:  99.62%
Target:  

VDAC Ferroptosis Disulfidptosis

Research Areas:  

Cancer

Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity. Furthermore, Erastin can block the uptake of cystine mediated by SLC7A11 and also spares UMRC6-EV and -C91A cells from disulfidptosis under glucose starvation .
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891
H2DCFDA
H2DCFDA
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891 Cited Publications
Cat. No.: HY-D0940
CAS No.: 4091-99-0
Synonyms: DCFH-DA; 2',7'-Dichlorodihydrofluorescein diacetate
Target:  

Fluorescent Dye Reactive Oxygen Species (ROS)

Research Areas:  

Others

H2DCFDA (DCFH-DA) is a cell-permeable probe used to detect intracellular reactive oxygen species (ROS) (Ex/Em=492/517 nm) .
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881
Z-VAD-FMK
Z-VAD-FMK
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881 Cited Publications
Cat. No.: HY-16658B
CAS No.: 161401-82-7
Synonyms: Z-VAD(OH)-FMK
Target:  

Caspase Apoptosis RIP kinase Glutathione Peroxidase Reactive Oxygen Species (ROS)

Research Areas:  

Inflammation/Immunology Cancer

Z-VAD-FMK is a pan-caspase inhibitor and also an ICE-like protease inhibitor, which inhibits apoptosis by preventing the processing of CPP32 to its active form. Z-VAD-FMK sensitivity varies primarily due to differential expression of receptor-interacting protein 1 (RIP1). Z-VAD-FMK limits the cryopreservation-induced apoptosis by reducing caspase-3 activity of in vitro produced bovine embryos. Z-VAD-FMK is immunosuppressive in vitro and inhibits T cell proliferation without blocking the processing of caspase-8 and caspase-3. Z-VAD-FMK leads to a decrease in intracellular glutathione (GSH) with a concomitant increase in reactive oxygen species (ROS) levels in activated T cells. Z-VAD-FMK is due to oxidative stress via the depletion of GSH. Z-VAD-FMK can be used for the study of acute pancreatitis .
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215
Rotenone
Rotenone
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215 Cited Publications
Cat. No.: HY-B1756
CAS No.: 83-79-4
Category:  

Flavonoids Neurological Disease 500 - Internal Server Error | MedChemExpress

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