1474 Results for "

receptor-1

" in MedChemExpress (MCE) Product Catalog:
Products (1474)

1474 Results for "receptor-1" in MCE Product Catalog:

80
80 Publications Verification
Cat. No.: HY-13715
CAS No.: 51-41-2
Purity:  99.61%
Synonyms: Levarterenol; L-Noradrenaline
Norepinephrine (Levarterenol; L-Noradrenaline) is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
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80
80 Publications Verification
Cat. No.: HY-13715A
CAS No.: 329-56-6
Purity:  99.89%
Synonyms: Levarterenol hydrochloride; L-Noradrenaline hydrochloride
Norepinephrine (Levarterenol; L-Noradrenaline) hydrochloride is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
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80
80 Publications Verification
Cat. No.: HY-13715B
CAS No.: 108341-18-0
Purity:  99.96%
Synonyms: Levarterenol bitartrate monohydrate; L-Noradrenaline bitartrate monohydrate
Norepinephrine (Levarterenol; L-Noradrenaline) bitartrate monohydrate is a potent adrenergic receptor (AR) agonist. Norepinephrine activates α1, α2, β1 receptors .
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80
80 Publications Verification
Cat. No.: HY-13715C
CAS No.: 51-40-1
Purity:  99.76%
Synonyms: Levarterenol tartrate; L-Noradrenaline tartrate
Norepinephrine (Levarterenol; L-Noradrenaline) tartrate is a potent adrenergic receptor (AR) agonist. Norepinephrine tartrate activates α1, α2, β1 receptors .
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73
73 Cited Publications
Cat. No.: HY-B2227
CAS No.: 50-21-5
Synonyms: DL-Lactic acid; E-270
Lactic acid (DL-Lactic acid) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid is an oncometabolite and has immune protective role of lactate in anti-tumor immunity [1] . Lactic acid also has antimicrobial activity, which can be used as a food preservative .
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72
72 Cited Publications
Cat. No.: HY-B2227C
CAS No.: 996-31-6
Synonyms: DL-Lactic acid potassium; E-270 potassium
Lactic acid (DL-Lactic acid) potassium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid potassium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid potassium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity [1] . Lactic acid also potassium has antimicrobial activity, which can be used as a food preservative .
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72
72 Cited Publications
Cat. No.: HY-B2227A
CAS No.: 814-80-2
Synonyms: DL-Lactic acid calcium; E-270 calcium
Lactic acid (DL-Lactic acid) calcium is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid calcium is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid calcium is an oncometabolite and has immune protective role of lactate in anti-tumor immunity [1] . Lactic acid calcium also has antimicrobial activity, which can be used as a food preservative .
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72
72 Cited Publications
Cat. No.: HY-B2227B
CAS No.: 72-17-3
Synonyms: DL-Lactic acid sodium; E-270 sodium
Lactic acid (DL-Lactic acid) sodium (60% w/w in water) is a hydroxycarboxylic acid receptor 1 (HCAR1) activator and an epigenetic modulator inducing lysine residues lactylation. Lactic acid sodium (60% w/w in water) is a glycolysis end-product, bridging the gap between glycolysis and oxidative phosphorylation. Lactic acid sodium (60% w/w in water) is an oncometabolite and has immune protective role of lactate in anti-tumor immunity [1] . Lactic acid sodium (60% w/w in water) also has antimicrobial activity, which can be used as a food preservative .
This product has a content (w/w) of 60%, and 1 mL of the system contains 798 mg of Lactic acid sodium, i.e., a concentration of 798 mg/mL (i.e., 7.12 M).
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65
65 Cited Publications
Cat. No.: HY-15252
CAS No.: 266359-93-7
Purity:  99.87%
Synonyms: Repertaxin L-lysine salt
Target:  

CXCR

Reparixin L-lysine salt is an allosteric inhibitor of chemokine receptor 1/2 (CXCR1/2) activation.
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41
41 Cited Publications
Cat. No.: HY-100714A
CAS No.: 79055-68-8
Purity:  99.94%
Synonyms: D-APV; D-2-Amino-5-phosphonovaleric acid
Target:  

iGluR

Research Areas:  

Neurological Disease

D-AP5 (D-APV) is a selective and competitive NMDA receptor antagonist with a Kd of 1.4 μM. D-AP5 (D-APV) inhibits the glutamate binding site of NMDA receptors .
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36
36 Cited Publications
Cat. No.: HY-B0469
CAS No.: 71-58-9
Synonyms: Medroxyprogesterone 17-acetate; Farlutin
Medroxyprogesterone acetate is a widely used synthetic steroid by its interaction with progesterone, androgen and glucocorticoid receptors .
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36
36 Cited Publications
Cat. No.: HY-P0201
CAS No.: 33507-63-0
Synonyms: Neurokinin P
Substance P (Neurokinin P) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).
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36
36 Cited Publications
Cat. No.: HY-P0201A
CAS No.: 148470-19-3
Synonyms: Neurokinin P TFA
Substance P TFA (Neurokinin P TFA) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) [1].
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30
30 Cited Publications
Cat. No.: HY-10007
CAS No.: 284035-33-2
Purity:  99.94%
Synonyms: SB-262470A
Target:  

CaSR

Research Areas:  

Metabolic Disease

NPS-2143 (SB-262470A), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 (SB-262470A) blocks increases in cytoplasmic Ca 2+ concentrations (IC50=43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor .
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30
30 Cited Publications
Cat. No.: HY-10171
CAS No.: 324523-20-8
Purity:  99.98%
Synonyms: SB-262470A hydrochloride
Target:  

CaSR

Research Areas:  

Metabolic Disease

NPS-2143 hydrochloride (SB-262470A hydrochloride), an orally active calcilytic agent, is a selective and potent calcium ion-sensing receptor (CaSR) antagonist. NPS-2143 hydrochloride (SB-262470A hydrochloride) blocks increases in cytoplasmic Ca 2+ concentrations (IC50=43 nM) elicited by activating the Ca 2+ receptor in HEK 293 cells expressing the human Ca 2+ receptor .
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30
30 Cited Publications
Cat. No.: HY-N0168
CAS No.: 520-33-2
Hesperetin is a natural flavanone that can be found in citrus, and acts as a potent and orally active broad-spectrum inhibitor against human UGT activity. Hesperetin induces apoptosis via p38 MAPK activation. Hesperetin displays a range of bioactivities including antioxidant, anti-inflammatory, and anti-cancer. Hesperetin is found to induce cell-cycle arrest at G2/M phase. Hesperetin can reduce Bcl-2 and enhance BaxM. Hesperetin induces apoptosis through inhibiting NF-κB receptor .
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28
28 Cited Publications
Cat. No.: HY-116771A
CAS No.: 138908-40-4
Purity:  99.98%
Target:  

Adrenergic Receptor

Research Areas:  

Metabolic Disease

CL316243 is a highly potent selective β3-adrenoceptor agonist with a EC50 of 3 nM, but is an extremely poor to β1/2- receptors .CL316243 is a effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate . CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence .
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25
25 Cited Publications
Cat. No.: HY-P9903
CAS No.: 946414-94-4
Synonyms: BMS-936558; ONO-4538; MDX-1106

Target:  

PD-1/PD-L1

Research Areas:  

Infection Cancer

Nivolumab is a programmed death receptor-1 (PD-1) blocking human IgG4 antibody to treat advanced (metastatic) non-small cell lung cancer.
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25
25 Cited Publications
Cat. No.: HY-108496
CAS No.: 26993-30-6
Purity:  ≥99.0%
Synonyms: S1P
Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. Sphingosine-1-phosphate is an intracellular second messenger and mobilizes Ca 2+ as an extracellular ligand for G protein-coupled receptors . Sphingosine-1-phosphate is an important lipid mediator generated from Sphingomyelin (HY-113498) or other membrane phospholipids . Sphingosine-1-phosphate stimulates the DNA synthesis, cell proliferation and migration .
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24
24 Cited Publications
Cat. No.: HY-P70311
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Interleukin-18 receptor 1; IL-18R1; CDw218a; IL1RRP; IL-18R-alpha; CD218a
Species:  
Rat Mouse Human
Source:  
HEK293
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