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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
7 Results for "
receptor-mediated internalization
" in MedChemExpress (MCE) Product Catalog:
Products (7)
7 Results for "receptor-mediated internalization" in MCE Product Catalog:
Cat. No.: HY-P10374
CAS No.: 900518-62-9
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Cat. No.: HY-P10374A
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Cat. No.: HY-P4092
CAS No.: 386223-83-2
HN-1 is a tumor-specific internalizing peptide . HN-1 internalizes through receptor-mediated, energy-dependent, Clathrin-mediated endocytosis. HN-1 preferentially binds to invasive head and neck squamous cell carcinoma and is selectively internalized. HN-1 enhances the transfer of liposome-DNA complexes to head and neck squamous cell carcinoma. HN-1 can be used for research on head and neck squamous cell carcinoma .
Cat. No.: HY-160045
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AP1153 aptamer sodium is a DNA aptamer that specifically binds to the cholecystokinin receptor CCKBR (Kd: ~15 pM), but does not activate CCKBR-related signaling pathways. AP1153 aptamer sodium is internalized by pancreatic ductal adenocarcinoma (PDAC) cells in a receptor-mediated manner. AP1153 aptamer sodium can bioconjugate to the surface of fluorescent nanoparticles to facilitate nanoparticle delivery to PDAC tumors in vivo .
Cat. No.: HY-164290
CAS No.: 1367579-04-1
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Rhodady C10 (Compound C10) is a dynamin I GTPase inhibitor. Rhodady C10 blocks receptor-mediated endocytosis (IC50: 7 μM). Dynamin is involved in clathrin-independent endocytosis, phagocytosis, and caveolae internalization .
Cat. No.: HY-P0240F
CAS No.: 1373319-09-5
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FITC-Tuftsin is a fluorescent probe and a Tuftsin (HY-P0240) receptor ligand that enters macrophages via receptor-mediated internalization, and its uptake is enhanced under Lipopolysaccharides, from E. coli O111:B4 (LPS) (HY-D1056A1)-stimulated macrophage activation. FITC-Tuftsin is used for the study of macrophage-mediated inflammation .
Cat. No.: HY-P12263
CAS No.: 288307-57-3
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A5G27 is a laminin-derived peptide ligand and CD44 antagonist that binds to CD44, CD44v3, and CD44v6, driving receptor-mediated endocytosis and internalization into CD44-expressing cells. A5G27 alleviates mechanical hyperalgesia induced by substances such as carrageenan and Hyaluronidase. A5G27 exhibits antitumor activity. A5G27 can be used in research on cancer, inflammatory pain, and wound healing .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
