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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
2 Results for "
reductive methylation
" in MedChemExpress (MCE) Product Catalog:
Products (2)
2 Results for "reductive methylation" in MCE Product Catalog:
Target:
Research Areas:
OTS193320, a imidazo[1,2-a]pyridine compound, is a SUV39H2 methyltransferase activity inhibitor. OTS193320 decreases global histone H3 lysine 9 tri-methylation levels in breast cancer cells and triggers apoptotic cell death. Combination of OTS193320 with Doxorubicin (HY-15142A) results in reduction of γ-H2AX levels as well as cancer cell viability compared to a single agent OTS193320 or DOX .
Cat. No.: HY-E71728
Research Areas:
Methylated porcine trypsin is a serine protease, which is divided into two categories: heterologously methylated type and homogeneously recombinantly methylated type. Methylated porcine trypsin hydrolyzes the C-terminal peptide bonds of lysine and arginine, and can block autolytic sites via reductive methylation modification of lysine residues, thereby inhibiting autoproteolysis. Methylated porcine trypsin is applicable to protein-related research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
