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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
178 Results for "
regulatory subunit
" in MedChemExpress (MCE) Product Catalog:
Products (178)
178 Results for "regulatory subunit" in MCE Product Catalog:
17
17 Publications Verification
Cat. No.: HY-A0005
CAS No.: 123318-82-1
Research Areas:
Clofarabine, a nucleoside analogue for research of cancer, is a potent inhibitor of ribonucleotide reductase (IC50=65 nM) by binding to the allosteric site on the regulatory subunit .
9
9 Cited Publications
Cat. No.: HY-P80846
Synonyms: PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s
4
4 Cited Publications
Synonyms: Sephin1; IFB-088
Target:
Research Areas:
Icerguastat (Sephin1), a derivative of Guanabenz lacking the α2-adrenergic activity, is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). Icerguastat inhibits eIF2α dephosphorylation, thereby prolonging the protective response. Anti-prion effect .
4
4 Cited Publications
Cat. No.: HY-P80867
Synonyms: PIK3R1; GRB1; Phosphatidylinositol 3-kinase regulatory subunit alpha; PI3-kinase regulatory subunit alpha; PI3K regulatory subunit alpha; PtdIns-3-kinase regulatory subunit alpha; Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha; PI3-kinase s
3
3
2
Monobenzone is a potent skin depigmenting agent. Monobenzone induces depigmentation and exhibits good potential for vitiligo research. Monobenzone is a potent inhibitor of RNR (Ribonucleotide reductase) enzyme activity by targeting RRM2 (a regulatory small subunit M2 of RNR) protein, and thus has significant anti-leukemia efficacy in vitro and in vivo. Monobenzone inhibits acute myeloid leukemia (AML) cells proliferation and DNA synthesis, induces cell cycle arrest, and Apoptosis .
2
2 Cited Publications
Cat. No.: HY-P80460
Synonyms: FAK, FAK1, PTK2, Focal adhesion kinase 1, FADK 1, Focal adhesion kinase-related nonkinase, Protein phosphatase 1 regulatory subunit 71, Protein-tyrosine kinase 2, p125FAK, pp125FAK, FRNK, PPP1R71
1
1
1 Cited Publications
Cat. No.: HY-P701744
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PIK3R3; PI3-Kinase regulatory subunit Gamma; Phosphoinositide-3-Kinase regulatory subunit 3; PI3K regulatory subunit Gamma; Phosphatidylinositol 3-Kinase 55 KDa regulatory subunit Gamma; PI3-Kinase subunit P55-Gamma; Phosphatidylinositol 3-Kinase Regulato
Species:
Human
Source:
Sf9 insect cells
1
1 Cited Publications
Cat. No.: HY-P790098
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: PSMD14; 26S Proteasome regulatory subunit RPN11; Proteasome 26S subunit, Non-ATPase 14; Ubiquitin C-Terminal Hydrolase PSMD14; POH1; Testis Tissue Sperm-Binding Protein Li 69n; 26S Proteasome Non-ATPase regulatory subunit 14; 26S Proteasome regulatory Sub
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P7537
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: BCL2; Protein Phosphatase 1, regulatory subunit 50; BCL2 Apoptosis Regulator; B-Cell CLL/Lymphoma 2; Apoptosis Regulator Bcl-2; BCL2, Apoptosis Regulator; PPP1R50; BCL2 Protein; Bcl-2
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P72101
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: BCL2; Protein Phosphatase 1, regulatory subunit 50; BCL2 Apoptosis Regulator; B-Cell CLL/Lymphoma 2; Apoptosis Regulator Bcl-2; BCL2, Apoptosis Regulator; PPP1R50; BCL2 Protein; Bcl-2
Species:
Mouse
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P86571
Synonyms: PTK2; FAK; FAK1; Focal adhesion kinase 1; FADK 1; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK
1
1 Cited Publications
Cat. No.: HY-137640C
CAS No.: 925456-59-3
Target:
Research Areas:
Rp-8-Br-cAMPS sodium is an analog of cAMP and an inhibitor of PKA. Rp-8-Br-cAMPS sodium occupies cAMP binding sites on PKA type I regulatory subunits, thereby preventing PKA dissociation and activation. Rp-8-Br-cAMPS sodium can be used in the study of tumors and retrovirus-induced immune deficiency. Rp-8-Br-cAMPS sodium also inhibits insulin secretion .
1
1 Cited Publications
Cat. No.: HY-P72224
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: HDAC6; HD6; Histone Deacetylase 6; Protein Phosphatase 1, regulatory subunit 90; Tubulin-Lysine Deacetylase HDAC6; E3 Ubiquitin-Protein Ligase HDAC6; Protein Deacetylase HDAC6; Alpha-Tubulin Deacetylase HDAC6; KIAA0901; FLJ16239; PPP1R90; HDAC6 Protein; K
Species:
Human
Source:
E. coli
1
1 Cited Publications
Cat. No.: HY-P73543
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: VDR; Vitamin D Receptor; NR1I1; Nuclear Receptor Subfamily 1 Group I Member 1; 1,25-Dihydroxyvitamin D3 Receptor; Vitamin D3 Receptor; PPP1R163; Vitamin D (1,25-Dihydroxyvitamin D3) Receptor; Protein Phosphatase 1, regulatory subunit 163; 1,25-Dihydroxyvi
Species:
Human
Source:
Sf9 insect cells
Research Areas:
RA375 is a RPN13 (26S proteasome regulatory subunit) inhibitor. RA375 activates UPR signaling, ROS production and apoptosis. RA375 exhibits ten-fold greater activity against cancer lines than RA190, reflecting its nitro ring substituents and the addition of a chloroacetamide warhead .
Synonyms: Deoxythymidine 3′,5′-diphosphate tetrasodium; pdTp tetrasodium
Thymidine 3',5'-diphosphate (Deoxythymidine 3′,5′-diphosphate) tetrasodium is a selective inhibitor of staphylococcal nuclease and tudor domain containing 1 (SND1, the MicroRNA regulatory complex RISC subunit) and [3,5- 2H2] tyrosyl nuclease. Thymidine 3',5'-diphosphate tetrasodium has anti-tumor activity and can also be used as a catalyst in biochemical reactions .
Cat. No.: HY-18956
CAS No.: 13098-73-2
Synonyms: (E/Z)-Sephin1; (E/Z)-IFB-088
Target:
Research Areas:
(E/Z)-Icerguastat ((E/Z)-Sephin1) is a selective inhibitor of the phosphatase regulatory subunit PPP1R15A (R15A). (E/Z)-Icerguastat can be used for protein misfolding diseases research .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
