141 Results for "

release histamine

" in MedChemExpress (MCE) Product Catalog:
Products (141)

141 Results for "release histamine" in MCE Product Catalog:

399
Dimethyl sulfoxide, meets analytical specification of Ch.P.
Dimethyl sulfoxide, meets analytical specification of Ch.P.
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399 Publications Verification
Cat. No.: HY-Y0320
CAS No.: 67-68-5
Synonyms: DMSO, meets analytical specification of Ch.P.
Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.
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66
Dimethyl sulfoxide
Dimethyl sulfoxide
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66 Cited Publications
Cat. No.: HY-Y0320C
CAS No.: 67-68-5
Synonyms: DMSO
Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .
Low endotoxin, can be used in various biochemical experiments such as drug dissolution.
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14
Loratadine
Loratadine
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14 Cited Publications
Cat. No.: HY-17043
CAS No.: 79794-75-5
Synonyms: Loratidine; SCH 29851
Target:  

Flavivirus Dengue Virus Histamine Receptor

Research Areas:  

Infection Inflammation/Immunology Endocrinology Cancer

Loratadine (SCH-29851) is a selective inverse peripheral histamine H1-receptor agonist with an IC50 of >32 μM. Loratadine has anti-dengue-virus (DENV) activity. Loratadine can inhibit immunologic release of inflammatory mediators.
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14
Desloratadine
Desloratadine
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14 Cited Publications
Cat. No.: HY-B0539
CAS No.: 100643-71-8
Synonyms: Sch34117
Category:  

Disease Research Fields Endocrinology

Target:  

Histamine Receptor TNF Receptor Leukotriene Receptor

Desloratadine (Sch34117) is an orally active and selective H1 receptor antagonist (Ki=0.9 nM) with anti-inflammatory and anti-allergic activities. Desloratadine inhibits the release of histamine and LTC4 from human basophils and targets the regulatory signals of IL-4 and IL-13 production in basophils. Desloratadine significantly alleviates SAR symptoms in patients with concurrent asthma and can be used in the study of seasonal allergic rhinitis and chronic idiopathic urticaria .
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11
Cromolyn
Cromolyn
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11 Cited Publications
Cat. No.: HY-B1619
CAS No.: 16110-51-3
Synonyms: Cromoglycate; Cromoglicic acid; FPL-670 free acid
Target:  

GSK-3 NF-κB Amyloid-β

Research Areas:  

Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Cromolyn (Cromoglycate) is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn can be used in the research of bronchial asthma. In addition, Cromolyn has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
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11
Cromolyn disodium
Cromolyn disodium
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11 Cited Publications
Cat. No.: HY-B0320A
CAS No.: 15826-37-6
Synonyms: Cromoglycate disodium; Cromoglicic acid disodium; FPL-670
Target:  

GSK-3 NF-κB Amyloid-β

Research Areas:  

Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Cromolyn (Cromoglycate) disodium is an orally active GSK-3β inhibitor with an IC50 of 2.0 μM. Cromolyn disodium is also a mast cell stabilizer that can inhibit the release of mediators from mast cells, regulate reflex bronchoconstriction, and reduce non-specific bronchial hyperreactivity, and Cromolyn disodium can be used in the research of bronchial asthma. In addition, Cromolyn disodium has multiple activities such as anti-inflammatory, anti-allergic, anti-histamine, anti-cancer, and neuroprotective effects .
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8
Methyl paraben
Methyl paraben
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8 Cited Publications
Cat. No.: HY-N0349
CAS No.: 99-76-3
Synonyms: Methyl 4-hydroxybenzoate
Category:  

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