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3 Cited Publications

Target:

Research Areas:

Tricyclazole is a pentaketone melanin biosynthesis inhibitor and a unique fungicide for controlling rice blast. Tricyclazole alters the structure and function of fungal cell walls, reduces fungal pathogenicity and penetration, and causes dose-dependent liver damage in animals .

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2,6-Dimethoxy-1,4-benzoquinone

Cat. No.: HY-N1677

CAS No.: 530-55-2

Category:

Infection Quinones Metabolic Disease Benzene Quinones Plants Other Families Extract Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Akt mTOR Bacterial Fungal AMPK

2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H₂O₂ generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness .

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Isotianil

Cat. No.: HY-W075256

CAS No.: 224049-04-1

Target:

Environmental Pollutants Bacterial

Research Areas:

Others

Isotianil is a plant defense inducer that has no direct antimicrobial effect but instead activates typical plant defense responses. Isotianil can be used as a plant protection agent for controlling rice blast .

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1,16-Hexadecanediol

Cat. No.: HY-W105735

CAS No.: 7735-42-4

Synonyms: Hexadecamethylene glycol

Target:

Fungal Mps1

Research Areas:

Infection

1,16-Hexadecanediol (Hexadecamethylene glycol) is a diol compound derived from plant wax and an inducer of appressorium formation in Magnaporthe grisea. Its activities include reversing PepEST-mediated inhibition and promoting the accumulation of α-1,3-glucan (a-1,3-glucan) on germ tubes and appressoria. 1,16-Hexadecanediol activates the Mps1 MAP kinase pathway through Mps1p phosphorylation. 1,16-Hexadecanediol can be used for research on rice blast and anthracnose .

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Orysastrobin

Cat. No.: HY-111968

CAS No.: 248593-16-0

Purity: 95.80%

Target:

Fungal

Research Areas:

Infection

Orysastrobin, a “quinone outside inhibitor” (QoI)-type fungicide, has excellent fungicidal efficacy against leaf and panicle blast and against sheath blight in rice .

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Feruloyl esterase

Cat. No.: HY-E70115

CAS No.: 134712-49-5

Target:

Fungal Bacterial

Research Areas:

Infection

Feruloyl esterase is a subclass of carboxylesterases that hydrolyzes the ester linkages between hydroxycinnamic acids and arabinoxylan/pectin polysaccharides in plant cell walls. Feruloyl esterase can hydrolyze ethyl ferulate to release ferulic acid, disrupt plant cell wall structure, promote fiber swelling, and facilitate cellulase hydrolysis. Feruloyl esterase synergizes with xylanase by removing ferulic acid side chains, thereby promoting efficient hydrolysis of xylan into monomers. Feruloyl esterase acts as a virulence factor for Verticillium dahliae VdFAE and Magnaporthe oryzae Fae1, facilitating host infection and colonization. Feruloyl esterase promotes the degradation of cotton GhDFR through binding to its NADPH domain, thereby inhibiting flavonoid-mediated innate immunity and inducing cell death in Nicotiana benthamiana. Feruloyl esterase can be used in studies related to verticillium wilt and rice blast .

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