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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
sarbecovirus
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "sarbecovirus" in MCE Product Catalog:
6
6 Cited Publications
Cat. No.: HY-P99340
CAS No.: 2423014-07-5
Synonyms: VIR-7831 (WT IgG1); GSK-4182136 (WT IgG1)
Sotrovimab (VIR-7831) (WT IgG1) is a human IgG1κ monoclonal antibody targeting the Sarbecovirus subgenus; it is capable of neutralizing SARS-CoV-2, SARS-CoV-1, and various other coronaviruses. Sotrovimab (WT IgG1) is a monoclonal antibody that retains the native, wild-type IgG1 Fc structure without any engineered modifications; unlike Sotrovimab (HY-P99340A), it does not contain the M428L or N434S mutations. Sotrovimab (WT IgG1) can be used for research on COVID-19 .
3
3 Cited Publications
Target:
Research Areas:
STING agonist-22 (CF501) is a potent non-nucleotide STING agonist. STING agonist-22 is a adjuvant by activating STING to induce the type I interferon (IFN-I) response and proinflammatory cytokine production. STING agonist-22 can be used as an adjuvant to boost the original protein vaccine, producing potent, broad, and long-term immune protection. STING agonist-22 can be used for SARS-CoV-2 variants and sarbecovirus diseases research .
Cat. No.: HY-173521
CAS No.: 3026520-19-1
Target:
Research Areas:
JNJ-9676 is an orally active Coronavirus M protein inhibitor and selective Sarbecovirus inhibitor. JNJ-9676 binds to the M protein dimer and forces the protein into an alternative conformational state with a compound-induced binding pocket. JNJ-9676 demonstrates in vitro nanomolar antiviral activity against SARS-CoV-2, SARS-CoV and Sarbecovirus strains from bat and pangolin zoonotic origin .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
