21

DOTAP methylsulfate

21 Publications Verification

Cat. No.: HY-W127378

CAS No.: 144189-73-1

Synonyms: 1,2-Dioleoyl-3-trimethylammonium-propane methylsulfate

Target:

Liposome

Research Areas:

Others

DOTAP methylsulfat is a cationic lipid reagent, a cationic derivative of trimethylammonium, linked to two 18-carbon fatty acid tails, each with a single olefin group. DOTAP methylsulfat can self-assemble with negatively charged ions (such as DNA) to form complexes, which can be adsorbed to the cell membrane surface and enter the cell by electrostatic interaction and endocytosis, respectively. DOTAP methylsulfat promotes endosomal membrane fusion with its own hydrophobic domain, releases DNA into the cytoplasm, and exerts gene delivery function. DOTAP methylsulfat can be widely used in research fields such as gene therapy, cell transfection, and non-viral vector design .

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14

α-Lipoic Acid

14 Cited Publications

Cat. No.: HY-N0492

CAS No.: 1077-28-7

Synonyms: Thioctic acid; (±)-α-Lipoic acid; DL-α-Lipoic acid

Category:

Infection Ketones, Aldehydes, Acids Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis

α-Lipoic Acid (Thioctic acid) is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

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14

α-Lipoic Acid sodium

14 Cited Publications

Cat. No.: HY-N0492A

CAS No.: 2319-84-8

Synonyms: Thioctic acid sodium; (±)-α-Lipoic acid sodium; DL-α-Lipoic acid sodium

Category:

Infection Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology Cancer

Target:

NF-κB HIV Mitochondrial Metabolism Endogenous Metabolite Apoptosis

α-Lipoic Acid (Thioctic acid) sodium is an antioxidant, which is an essential cofactor of mitochondrial enzyme complexes. α-Lipoic Acid sodium inhibits NF-κB-dependent HIV-1 LTR activation . α-Lipoic Acid sodium induces endoplasmic reticulum (ER) stress-mediated apoptosis in hepatoma cells . α-Lipoic Acid sodium can be used with CPUL1 (HY-151802) to construct the self-assembled nanoaggregate CPUL1-LA NA, which has improved antitumor efficacy than CPUL1 .

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2

DOTA-NHS-ester

2 Cited Publications

Cat. No.: HY-128890

CAS No.: 170908-81-3

Purity: ≥95.0%

Target:

Biochemical Assay Reagents

Research Areas:

Cancer

DOTA-NHS-ester is a bifunctional reagent containing a DOTA chelating group and an NHS ester. DOTA-NHS-ester can be conjugated to proteins/antibodies/HSA via primary amino groups for radiolabeling with radiometals, and when combined with 16-amino-1-hexadecanethiol hydrochloride, it enables the construction of self-assembled monolayers on gold surfaces for lectin microarrays. DOTA-NHS-ester can be used to prepare DOTA-HSA-Z (HER2:342) imaging probes, as well as to construct Trop2-targeted radiotherapeutic and diagnostic probes for pancreatic cancer .

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2

DOTA-NHS-ester TFA

2 Cited Publications

Cat. No.: HY-128890B

Purity: 95.00%

Target:

Biochemical Assay Reagents

Research Areas:

Cancer

DOTA-NHS-ester TFA is a bifunctional reagent containing a DOTA chelating group and an NHS ester. DOTA-NHS-ester TFA can be conjugated to proteins/antibodies/HSA via primary amino groups for radiolabeling with radiometals, and when combined with 16-amino-1-hexadecanethiol hydrochloride, it enables the construction of self-assembled monolayers on gold surfaces for lectin microarrays. DOTA-NHS-ester TFA can be used to prepare DOTA-HSA-Z (HER2:342) imaging probes, as well as to construct Trop2-targeted radiotherapeutic and diagnostic probes for pancreatic cancer .

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1

Aminopropyltrimethoxysilane

1 Cited Publications

Cat. No.: HY-W036410

CAS No.: 13822-56-5

Synonyms: 3-Aminopropyltrimethoxysilane; APTMS

Target:

Biochemical Assay Reagents

Research Areas:

Others

Aminopropyltrimethoxysilane (3-Aminopropyltrimethoxysilane; APTMS) is an aminosilane coupling agent and self-assembled molecule that can form self-assembled monolayers or multilayers on the surfaces of silicon-based materials, platinum, pullulan (Viscosity (10%): 15-180 mPa.s) (HY-W145522), and magnesium alloys through silanization or amine-mediated adsorption, serving for surface functionalization and performance regulation. Aminopropyltrimethoxysilane is applicable in research related to biomedical materials, antibacterial materials, and corrosion protection .

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1

PLGA38000-PEG10000

1 Cited Publications

Cat. No.: HY-176499

Target:

Biochemical Assay Reagents

Research Areas:

Others

PLGA38000-PEG10000 is an amphiphilic polymer. Amphiphilic polymers can be used in drug delivery studies due to their ability to self-assemble into discrete aggregates .

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1

Aleuritic acid

1 Cited Publications

Cat. No.: HY-N7076

CAS No.: 533-87-9

Synonyms: (±)-erythro-Aleuritic acid; α-Aleuritic acid

Category:

Ketones, Aldehydes, Acids Other Diseases 500 - Internal Server Error | MedChemExpress

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