6096 Results for "

side effect reduction

" in MedChemExpress (MCE) Product Catalog:

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1851

Ferrostatin-1

1851 Publications Verification

Cat. No.: HY-100579

CAS No.: 347174-05-4

Purity: 99.71%

Synonyms: Fer-1

Target:

Ferroptosis Fungal

Research Areas:

Cancer

Ferrostatin-1 (Fer-1), a potent and selective ferroptosis inhibitor, suppresses Erastin-induced ferroptosis in HT-1080 cells (EC₅₀=60 nM). Ferrostatin-1, a synthetic antioxidant, acts via a reductive mechanism to prevent damage to membrane lipids and thereby inhibits cell death. Ferrostatin-1 exhibits antifungal activity .

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1371

3-Methyladenine

1371 Cited Publications

Cat. No.: HY-19312

CAS No.: 5142-23-4

Synonyms: 3-MA

Category:

Natural Products Microorganisms Endogenous metabolite Disease Research Fields Cancer

Target:

PI3K Autophagy Mitophagy Endogenous Metabolite

3-Methyladenine (3-MA) is a PI3K inhibitor. 3-Methyladenine is a widely used inhibitor of autophagy via its inhibitory effect on class III PI3K .

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843

Dorsomorphin dihydrochloride

843 Cited Publications

Cat. No.: HY-13418

CAS No.: 1219168-18-9

Purity: 99.7%

Synonyms: BML-275 dihydrochloride; Compound C dihydrochloride

Target:

Organoid AMPK TGF-β Receptor Autophagy

Research Areas:

Neurological Disease Metabolic Disease Inflammation/Immunology Cancer

Dorsomorphin (Compound C) dihydrochloride is a potent, selective and ATP-competitive AMPK inhibitor, with a K_i of 109 nM. Dorsomorphin dihydrochloride inhibits BMP pathway by targeting the type I receptors ALK2, ALK3, and ALK6. Dorsomorphin dihydrochloride can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599).

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843

Dorsomorphin

843 Cited Publications

Cat. No.: HY-13418A

CAS No.: 866405-64-3

Purity: 99.10%

Synonyms: BML-275; Compound C

Target:

Organoid AMPK TGF-β Receptor Autophagy

Research Areas:

Inflammation/Immunology Cancer

Dorsomorphin (BML-275; Compound C) is a selective and ATP-competitive AMPK inhibitor (K_i=109 nM in the absence of AMP). Dorsomorphin selectively inhibits BMP type I receptors ALK2, ALK3, and ALK6. Dorsomorphin can reverse autophagy activation and anti-inflammatory effect of Urolithin A (HY-100599) .

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