15 Results for "

sirtuin-1

" in MedChemExpress (MCE) Product Catalog:
Products (15)

15 Results for "sirtuin-1" in MCE Product Catalog:

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7
SRT 1460
SRT 1460
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7 Publications Verification
Cat. No.: HY-124037
CAS No.: 925432-73-1
Purity:  98.16%
Target:  

Sirtuin

Research Areas:  

Cancer

SRT 1460, a potent Sirtuin-1 (SIRT1) activator with an EC1.5 value of 2.9 μM, shows good selectivity for activation of SIRT1 versus SIRT2 and SIRT3 (EC1.5>300 μM), and is more potent than Resveratrol and the closest sirtuin homologues [1].
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5
SIRT1 Protein, Human (His)
SIRT1 Protein, Human (His)
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5 Cited Publications
Cat. No.: HY-P71596
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SIRT1; sirtuin (Silent Mating Type Information Regulation 2, S. Cerevisiae, Homolog) 1; sirtuin 1; sirtuin (Silent Mating Type Information Regulation 2 Homolog) 1 (S. Cerevisiae); SIR2L1; Protein Acetyllysine N-Acetyltransferase; NAD-Dependent Protein Dea
Species:  
Human
Source:  
E. coli
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4
SRT 2183
SRT 2183
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4 Cited Publications
Cat. No.: HY-19759
CAS No.: 1001908-89-9
Target:  

Sirtuin Apoptosis

Research Areas:  

Cancer

SRT 2183 is a selective Sirtuin-1 (SIRT1) activator with an EC1.5 value of 0.36 μM [1]. SRT 2183 induces growth arrest and apoptosis, concomitant with deacetylation of STAT3 and NF-κB, and reduction of c-Myc protein levels .
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4
SIRT1 Antibody (YA082)
SIRT1 Antibody (YA082)
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4 Cited Publications
Cat. No.: HY-P80319
Synonyms: SIRT1; SIR2L1; NAD-dependent protein deacetylase sirtuin-1; hSIRT1; Regulatory protein SIR2 homolog 1; SIR2-like protein 1; hSIR2; sirtuin 1

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF, ChIP

Reactivity:  

Human, Mouse

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1
E1231
E1231
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1 Cited Publications
Cat. No.: HY-117006
CAS No.: 1031195-19-3
Purity:  98.55%
Synonyms: 1-{4-[2-(5-Methylfuran-2-yl)quinoline-4-carbonyl]piperazin-1-yl}ethan-1-one
Target:  

Sirtuin

Research Areas:  

Cardiovascular Disease

E1231 is an orally active activator of Sirtuin 1 (SIRT1) (EC50=0.83 μM), to modulate cholesterol and lipid metabolism. E1231 interactes with SIRT1 (KD=9.61 μM) and deacetylated liver X receptor-alpha (LXRα), and increases ATP-binding cassette transporter A1 (ABCA1) expression. E1231 also reduces atherosclerotic plaque development in ApoE -/- mice model. E1231 can be used for research in cholesterol and lipid disorder-related diseases [1].
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Sirtuin-1 inhibitor 1
Sirtuin-1 inhibitor 1
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Cat. No.: HY-156781
CAS No.: 945114-10-3
Purity:  98.09%
Target:  

Sirtuin

Research Areas:  

Metabolic Disease

Sirtuin-1 inhibitor 1 (Compound 8) is an inhibitor of Sirtuin-1 that plays important roles in obesity-induced diabetes and aging-related diseases [1].
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Myricanol
Myricanol
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Cat. No.: HY-N3225
CAS No.: 33606-81-4
Category:  

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