169 Results for "

sodium intercalator

" in MedChemExpress (MCE) Product Catalog:
Products (169)

169 Results for "sodium intercalator" in MCE Product Catalog:

32
EthD bromide
EthD bromide
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32 Publications Verification
Cat. No.: HY-D0021
CAS No.: 1239-45-8
Synonyms: EtBr; Homidium bromide
EthD bromide is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
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15
BMH-21
BMH-21
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15 Cited Publications
Cat. No.: HY-12484
CAS No.: 896705-16-1
Purity:  99.25%
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

BMH-21 is a first-in-class DNA intercalator which inhibits RNA polymerase I (Pol I) transcription. BMH-21 possesses anticancer activity .
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15
Diminazene aceturate
Diminazene aceturate
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15 Cited Publications
Cat. No.: HY-12404
CAS No.: 908-54-3
Purity:  99.16%
Synonyms: Diminazene diaceturate
Target:  

Parasite Angiotensin-converting Enzyme (ACE)

Research Areas:  

Infection Inflammation/Immunology

Diminazene aceturate (Diminazene diaceturate) is an anti-trypanosome agent for livestock. The main biochemical mechanism of the trypanocidal actions of Diminazene aceturate is by binding to trypanosomal kinetoplast DNA (kDNA) in a non-intercalative manner through specific interaction with sites rich in adenine-thymine base pairs. Diminazene aceturate is also an angiotensin-converting enzyme 2 (ACE2) activator and has strong and potent anti-inflammatory properties .
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8
Amsacrine
Amsacrine
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8 Cited Publications
Cat. No.: HY-13551
CAS No.: 51264-14-3
Purity:  99.91%
Synonyms: m-AMSA; acridinyl anisidide
Target:  

Topoisomerase Autophagy

Research Areas:  

Cancer

Amsacrine (m-AMSA; acridinyl anisidide) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells.
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8
Amsacrine hydrochloride
Amsacrine hydrochloride
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8 Cited Publications
Cat. No.: HY-13551A
CAS No.: 54301-15-4
Purity:  99.92%
Synonyms: m-AMSA hydrochloride; acridinyl anisidide hydrochloride
Target:  

Topoisomerase Autophagy

Research Areas:  

Cancer

Amsacrine hydrochloride (m-AMSA hydrochloride; acridinyl anisidide hydrochloride) is an inhibitor of topoisomerase II, and acts as an antineoplastic agent which can intercalates into the DNA of tumor cells.
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6
Bisantrene
Bisantrene
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6 Cited Publications
Cat. No.: HY-100875
CAS No.: 78186-34-2
Purity:  98.08%
Synonyms: CL216942
Target:  

Topoisomerase

Research Areas:  

Cancer

Bisantrene is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene targets eukaryotic type II topoisomerases. Bisantrene is a substrate of MDR1 .
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6
Bisantrene dihydrochloride
Bisantrene dihydrochloride
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6 Cited Publications
Cat. No.: HY-100875A
CAS No.: 71439-68-4
Purity:  98.86%
Synonyms: CL-216942 dihydrochloride
Target:  

Topoisomerase

Research Areas:  

Cancer

Bisantrene dihydrochloride is a highly effective antitumor agent, it exerts its cytotoxicity by affecting DNA intercalation. Bisantrene dihydrochloride targets eukaryotic type II topoisomerases. Bisantrene dihydrochloride is a substrate of MDR1 .
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6
SYBR green I chloride
SYBR green I chloride
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6 Cited Publications
Cat. No.: HY-D1191
CAS No.: 2225748-05-8
SYBR Green I chloride is a highly sensitive fluorescent nucleic acid dye that binds specifically to the minor groove of double-stranded DNA or intercalates between base pairs. SYBR Green I chloride exhibits weak fluorescence in the unbound state but emits bright fluorescence upon binding, and it preferentially binds to large-fragment DNA and DNA with high G+C content. SYBR Green I chloride is suitable for real-time PCR technology; its fluorescence intensity correlates with the amount and size of amplification products, enabling accurate quantification of gene expression and discrimination of amplicons via melting curve analysis without additional post-processing. SYBR Green I chloride is widely used in preclinical in vitro nucleic acid detection .
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5
Amonafide
Amonafide
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5 Cited Publications
Cat. No.: HY-10982
CAS No.: 69408-81-7
Purity:  99.92%
Synonyms: AS1413
Target:  

Topoisomerase

Research Areas:  

Cancer

Amonafide is a topoisomerase II inhibitor and DNA intercalator that induces apoptotic signaling by blocking the binding of Topo II to DNA.
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4
2-(Pyridyldithio)ethylamine hydrochloride
2-(Pyridyldithio)ethylamine hydrochloride
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4 Cited Publications
Cat. No.: HY-101794
CAS No.: 106139-15-5
Purity:  99.93%
Synonyms: (S)-2-Pyridylthio Cysteamine Hydrochloride
2-(Pyridyldithio)ethylamine hydrochloride is a novel disulfide intercalating cross-linking reagent.
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4
Pyronin Y
Pyronin Y
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4 Cited Publications
Cat. No.: HY-D0971
CAS No.: 92-32-0
Synonyms: Pyronine G; C.I. 45005
Pyronin Y (Pyronine G) is a cationic dye that intercalates RNA and has been used to target cell structures including RNA, DNA and organelles. Pyronin Y forms fluorescent complexes with double-stranded nucleic acids (especially RNA) enabling semi-quantitative analysis of cellular RNA. Pyronin Y can be used to identify specific RNA subspecies of ribonuclear proteins complexes in live cells .
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3
Pixantrone
Pixantrone
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3 Cited Publications
Cat. No.: HY-13727A
CAS No.: 144675-97-8
Purity:  98.75%
Synonyms: BBR 2778
Target:  

Topoisomerase

Research Areas:  

Cancer

Pixantrone (BBR 2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity.
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3
Voreloxin
Voreloxin
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3 Cited Publications
Cat. No.: HY-10534
CAS No.: 175414-77-4
Purity:  99.26%
Synonyms: SNS-595; Vosaroxin; AG 7352
Target:  

Topoisomerase Apoptosis

Research Areas:  

Cancer

Voreloxin (SNS-595; Vosaroxin; AG 7352) is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.
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3
Ethidium bromide (solution)
Ethidium bromide (solution)
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3 Cited Publications
Cat. No.: HY-DY1050
CAS No.: 1239-45-8
Ethidium bromide (solution) is an intercalating agent commonly used as a fluorescent tag (nucleic acid stain) in molecular biology laboratories for techniques such as agarose gel electrophoresis.
Solvent and Concentration: Sterile water: 10 mg/Ml
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3
3,6-Diaminoacridine
3,6-Diaminoacridine
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3 Cited Publications
Cat. No.: HY-B1741
CAS No.: 92-62-6
Target:  

Bacterial Fluorescent Dye DNA/RNA Synthesis

Research Areas:  

Infection Cancer

3,6-Diaminoacridine is a versatile acridine compound. 3,6-Diaminoacridine exerts antibacterial activity by intercalating into bacterial DNA, interfering with replication and transcription, and inducing bacterial lysis. 3,6-Diaminoacridine is an acridine dye and also a DNA intercalator .
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3
Voreloxin Hydrochloride
Voreloxin Hydrochloride
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3 Cited Publications
Cat. No.: HY-16518
CAS No.: 175519-16-1
Synonyms: SNS-595 Hydrochloride; Vosaroxin Hydrochloride; AG 7352 Hydrochloride
Target:  

Topoisomerase Apoptosis

Research Areas:  

Cancer

Voreloxin Hydrochloride is a first-in-class topoisomerase II inhibitor that intercalates DNA and induces site-selective DNA DSB, G2 arrest, and apoptosis.
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3
Mitonafide
Mitonafide
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3 Cited Publications
Cat. No.: HY-119182
CAS No.: 54824-17-8
Purity:  99.79%
Synonyms: NSC 300288
Target:  

DNA/RNA Synthesis

Research Areas:  

Cancer

Mitonafide (NSC 300288) is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia .
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3
Anthraquinone
Anthraquinone
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3 Cited Publications
Cat. No.: HY-N0354
CAS No.: 84-65-1
Category:  

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