1 Result for "

spinal sensitization

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "spinal sensitization" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-18099A
CAS No.: 1265917-14-3
Synonyms: E-52862 hydrochloride
Research Areas:  

Neurological Disease

S1RA (E-52862) hydrochloride is an orally active and selective sigma-1 receptor (σ1R) antagonist with a Ki value of 17 nM. S1RA hydrochloride shows good selectivity against σ2R (Ki >1000 nM). S1RA hydrochloride is a human 5-HT2B receptor antagonist with an IC50 value of 4.7 μM. S1RA hydrochloride inhibits neuropathic pain and activity-induced spinal sensitization .
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