130 Results for "

splice variant

" in MedChemExpress (MCE) Product Catalog:
Products (130)

130 Results for "splice variant" in MCE Product Catalog:

122
122 Publications Verification
Cat. No.: HY-12248
CAS No.: 1439399-58-2
Purity:  99.82%
Synonyms: CB-839
Target:  

Glutaminase Autophagy

Research Areas:  

Cancer

Telaglenastat (CB-839) is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat inuduces autophagy and has antitumor activity .
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122
122 Publications Verification
Cat. No.: HY-12248A
CAS No.: 1874231-60-3
Synonyms: CB-839 hydrochloride
Target:  

Glutaminase Autophagy

Research Areas:  

Cancer

Telaglenastat (CB-839) hydrochloride is a first-in-class, selective, reversible and orally active glutaminase 1 (GLS1) inhibitor. Telaglenastat hydrochloride selectively inhibits GLS1 splice variants KGA (kidney-type glutaminase) and GAC (glutaminase C) compared to GLS2. The IC50s are 23 nM and 28 nM for endogenous glutaminase in mouse kidney and brain, respectively. Telaglenastat hydrochloride inudces autophagy and has antitumor activity .
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10
10 Cited Publications
Cat. No.: HY-P70593
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: FN1; Epididymis Secretory Sperm Binding Protein; Fibronectin 1; Fibronectin splice variant A; CIG; Fibronectin splice variant B; Cold-Insoluble Globulin; Fibronectin splice variant C; Lnc-ABCA12-8; Fibronectin splice variant D; Fibronectin; Fibronectin splice variant E; GFND2; Fibronectin splice variant F; LETS; FN1 Protein; FINC; SMDCF; MSF; ED-B; Migration-Stimulating Factor; GFND; FN; FNZ
Species:  
Human
Source:  
E. coli
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5
5 Cited Publications
Cat. No.: HY-N1943
CAS No.: 981-15-7
Synonyms: Δ13-Dehydrochaparrinone
Category:  

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