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3 Cited Publications

Category:

Alkaloids Human Gut Microbiota Metabolites Microorganisms Metabolic Disease Endogenous metabolite Disease Research Fields Indole Alkaloids

Target:

Endogenous Metabolite

Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .

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Chlorobutanol

Cat. No.: HY-B1263

CAS No.: 57-15-8

Target:

Environmental Pollutants Bacterial Fungal

Research Areas:

Infection Neurological Disease

Chlorobutanol is an orally active and potent inhibitor of platelet aggregation and release and a pharmaceutical preservative with antibacterial activity. Chlorobutanol inhibits thromboxane B2 formation, ATP release, and elevation of cytosolic free calcium caused by collagen, ADP, epinephrine, arachidonic acid and thrombin. Chlorobutanol is active against a wide variety of Gram-positive and Gram-negative bacteria, and several mold spores and fungi. Chlorobutanol is widely used in food and cosmetic industry .

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2,6-Dimethoxy-1,4-benzoquinone

Cat. No.: HY-N1677

CAS No.: 530-55-2

Category:

Infection Quinones Metabolic Disease Benzene Quinones Plants Other Families Extract Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:

Akt mTOR Bacterial Fungal AMPK

2,6-Dimethoxy-1,4-benzoquinone is a 1,4-benzoquinone derivative. 2,6-Dimethoxy-1,4-benzoquinone promotes phosphorylation of AKT, S6K, mTOR, 4E-BP1, and AMPK, and attenuates mTORC1 activity as part of the AKT/mTOR pathway. 2,6-Dimethoxy-1,4-benzoquinone stimulates myoblast differentiation, increases myotube size, elevates MHC protein expression, enhances mitochondrial biogenesis, respiration, and DNA content, and increases skeletal muscle weights, fiber size, grip strength, and treadmill performance. 2,6-Dimethoxy-1,4-benzoquinone exerts anti-cancer, anti-inflammatory, anti-adipogenic, antibacterial, and antimutagenic effects, inhibits adipogenic transcription factors, nitric oxide production, skin tumor development, Magnaporthe oryzae growth, spore germination, appressorium formation, and growth of select bacterial species, induces H₂O₂ generation and rice defense gene expression, and reduces rice blast lesion formation. 2,6-Dimethoxy-1,4-benzoquinone can be used for the research of obesity, skin tumorigenesis, rice blast disease, and food-borne illness .

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MGB-BP-3

Cat. No.: HY-U00035

CAS No.: 1000277-08-6

Target:

Bacterial DNA Alkylator/Crosslinker

Research Areas:

Infection

MGB-BP-3 is an orally aective Gram-positive bactericide and DNA-binding agent. MGB-BP-3 blocks transcription initiation by binding to AT-rich bacterial DNA regions, and interferes with the functions of DNA gyrase and topoisomerase IV, but does not stabilize cleavage complexes or induce the SOS response. MGB-BP-3 induces energy depletion in *Staphylococcus aureus* and inhibits spore formation in *Clostridioides difficile*, exhibiting intrinsic resistance resilience. MGB-BP-3 can be used in the research of *Clostridioides difficile*-associated diseases .

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Indole (standard)

Cat. No.: HY-W001132R

CAS No.: 120-72-9

Category:

Alkaloids Human Gut Microbiota Metabolites Natural Products Microorganisms Endogenous metabolite Indole Alkaloids

Target:

Reference Standards Endogenous Metabolite

Indole (Standard) is the analytical standard of Indole. This product is intended for research and analytical applications. Indole is an aromatic, heterocyclic, organic compound which widely distributed in the natural environment and can be produced by a variety of bacteria. Indole regulates various aspects of bacterial physiology, including spore formation, plasmid stability, resistance to drugs, biofilm formation, and virulence as an intercellular signal molecule .

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DL-m-Tyrosine

Cat. No.: HY-W001940

CAS No.: 775-06-4

Category:

Cardiovascular Disease Monophenols Animals Ketones, Aldehydes, Acids Phenols Disease Research Fields

Target:

Amino Acid Derivatives Bacterial

DL-m-Tyrosine is a non-protein amino acid. DL-m-Tyrosine inhibits microbial growth and spore formation. DL-m-Tyrosine also inhibits root growth in various plants, such as lettuce and Arabidopsis. DL-m-Tyrosine, when used in combination with Carbidopa (HY-B0311), has a potent antihypertensive effect. DL-m-Tyrosine can be used in research on biopesticide design .

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