399

Dimethyl sulfoxide, meets analytical specification of Ch.P.

399 Publications Verification

Synonyms: DMSO, meets analytical specification of Ch.P.

Dimethyl sulfoxide (DMSO), meets analytical specification of Ch.P. is an aprotic solvent that dissolves polar and non-polar compounds, including water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and can rapidly penetrate or enhance the penetration of other substances into biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity. Dimethyl sulfoxide also exhibits antifreeze and antibacterial properties .
MCE provides Dimethyl sulfoxide that complies with the inspection standards (Ch.P) of Part 4 of the Chinese Pharmacopoeia (2020 Edition). Amicrobic, low endotoxin, can be used in various biochemical experiments such as drug dissolution.

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131

Methyl-β-cyclodextrin

131 Cited Publications

Cat. No.: HY-101461

CAS No.: 128446-36-6

Purity: 99.95%

Synonyms: Methyl-beta-cyclodextrin

Methyl-β-cyclodextrin (Methyl-beta-cyclodextrin) is a cyclic heptasaccharide used to deliver hydrophobic agents based on its property of solubilizing non-polar substances. Methyl-β-cyclodextrin is also extensively used as a cholesterol-depleting reagent . Methyl-β-cyclodextrin strongly reduces clathrin-dependent endocytosis . Methyl-β-cyclodextrin blocks cell migrasome formation .

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66

Dimethyl sulfoxide

66 Cited Publications

Cat. No.: HY-Y0320C

CAS No.: 67-68-5

Synonyms: DMSO

Dimethyl sulfoxide (DMSO) is an aprotic solvent that can dissolve water-insoluble therapeutic and toxic agents. Dimethyl sulfoxide (DMSO) has a strong affinity for water and has the ability to rapidly penetrate or enhance the penetration of other substances through biological membranes. Dimethyl sulfoxide also has potential free radical scavenging and anticholinesterase effects and may affect coagulation activity. Dimethyl sulfoxide also induces histamine release from mast cells but is thought to have low systemic toxicity .
Low endotoxin, can be used in various biochemical experiments such as drug dissolution.

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64

Prostaglandin E2

64 Cited Publications

Cat. No.: HY-101952

CAS No.: 363-24-6

Purity: 99.74%

Synonyms: PGE2; Dinoprostone

Category:

Ketones, Aldehydes, Acids Disease markers Nervous System Disorder Endogenous metabolite Disease Research Fields Endocrinology

Target:

Organoid Prostaglandin Receptor Endogenous Metabolite

Prostaglandin E2 (PGE2) is a hormone-like substance that participate in a wide range of body functions such as the contraction and relaxation of smooth muscle, the dilation and constriction of blood vessels, control of blood pressure, and modulation of inflammation.

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45

PEG400

45 Cited Publications

Cat. No.: HY-Y0873A

CAS No.: 25322-68-3

Synonyms: Polyethylene glycol 400

PEG400 is a strongly hydrophilic polyethylene glycol used as an excellent solvent for a large number of substances. PEG400 is widely used in a variety of pharmaceutical formulations.

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36

Substance P

36 Cited Publications

Cat. No.: HY-P0201

CAS No.: 33507-63-0

Synonyms: Neurokinin P

Category:

Natural Products Neurological Disease Endogenous metabolite Disease Research Fields Endocrinology

Target:

Neurokinin Receptor Endogenous Metabolite

Substance P (Neurokinin P) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R).

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36

Substance P TFA

36 Cited Publications

Cat. No.: HY-P0201A

CAS No.: 148470-19-3

Synonyms: Neurokinin P TFA

Target:

Neurokinin Receptor Endogenous Metabolite

Research Areas:

Neurological Disease Metabolic Disease Cancer

Substance P TFA (Neurokinin P TFA) is a CNS-penetrant neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P is neurokinin 1 receptor (NK1-receptor, NK1R) .

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18

Ruthenium red

18 Cited Publications

Cat. No.: HY-103311

CAS No.: 11103-72-3

Purity: ≥97.0%

Synonyms: Ammoniated ruthenium oxychloride

Target:

Calcium Channel

Research Areas:

Cardiovascular Disease

Ruthenium red (Ammoniated ruthenium oxychloride) is a polycationic dye widely used for electron microscopy (EM) of cells, tissues and vegetative bacteria. Ruthenium red strongly reacts with phospholipids and fatty acids and binds to acidic mucopolysaccharides. Ruthenium red is a L-type calcium current (I_Ca) blocker. When using Ruthenium Red to stain plant tissue sections affected by pathogens, the breakdown of mucilaginous substances by the pathogens prevents them from taking up the stain, whereas the cell walls of healthy tissue stain red .

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14

Mevalonic acid lithium salt

14 Cited Publications

Cat. No.: HY-113071A

CAS No.: 2618458-93-6

Purity: ≥98.0%

Synonyms: MVA lithium salt

Category:

Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields

Target:

Endogenous Metabolite

Mevalonic acid (MVA) lithium salt is a precursor substance of the mevalonate pathway, which is essential for cell growth and proliferation. Mevalonic acid lithium salt is effective in inhibiting Simvastatin (HY-17502)-induced decrease in C2C12 cell viability in vitro. Mevalonic acid lithium salt can be used in studies of myopathy and heart failure .

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12

Taurochenodeoxycholic acid sodium

12 Cited Publications

Cat. No.: HY-N1429

CAS No.: 6009-98-9

Synonyms: 12-Deoxycholyltaurine sodium

Category:

Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids

Target:

Apoptosis Endogenous Metabolite

Taurochenodeoxycholic acid (12-Deoxycholyltaurine) sodium is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and immune regulation properties .

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12

Taurochenodeoxycholic acid

12 Cited Publications

Cat. No.: HY-N2027

CAS No.: 516-35-8

Synonyms: 12-Deoxycholyltaurine

Category:

Endogenous metabolite Disease Research Fields Inflammation/Immunology Steroids

Target:

Caspase Apoptosis Endogenous Metabolite

Taurochenodeoxycholic acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid induces apoptosis and shows obvious anti-inflammatory and immune regulation properties .

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8

Hypericin

8 Cited Publications

Cat. No.: HY-N0453

CAS No.: 548-04-9

Category:

Quinones Anthraquinones Guttiferae Extract 500 - Internal Server Error | MedChemExpress

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