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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
18 Results for "
succinate oxidation
" in MedChemExpress (MCE) Product Catalog:
Products (18)
18 Results for "succinate oxidation" in MCE Product Catalog:
7
7 Publications Verification
Synonyms: Methylmaleic acid; Citraconate
1
1 Cited Publications
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1 Cited Publications
Synonyms: Dichlorophenylindophenol sodium; DCPIP sodium; Indochlorophenol sodium
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1 Cited Publications
Category:
Plant Orchidaceae Extract Ketones, Aldehydes, Acids Other Diseases Bletilla striata (Thunb. ex Murray) Rchb. f. Extract Disease Research Fields
Target:
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Cat. No.: HY-162142
CAS No.: 2226086-65-1
Research Areas:
BB2-50F is an antimicrobial agent and succinate dehydrogenase and F1Fo-ATP synthase inhibitor. BB2-50F induces ROS. BB2-50F inhibits succinate oxidation and reduces tricarboxylic acid (TCA) cycle activity. BB2-50F inhibits the growth of Mycobacterium tuberculosis H37Rv and its auxotrophic, attenuated derivative mc2 6230 (ΔRD1, ΔpanCD) with an MIC of 8 μM .
Target:
Research Areas:
Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity .
Cat. No.: HY-W007894R
CAS No.: 595-46-0
Synonyms: Dimethylpropanedioic acid (Standard)
Cat. No.: HY-114509R
CAS No.: 101-05-3
Target:
Research Areas:
Anilazine (Standard) is the analytical standard of Anilazine. This product is intended for research and analytical applications. Anilazine is a fungicide and inhibit the growth of Rhizobium sp. and E. coli. Anilazine inhibits glucose oxidation and succinate oxidation and also inhibits in vitro succinic dehydrogenase activity .
Cat. No.: HY-157459
CAS No.: 2998946-58-8
SDH-IN-11 (compound A7) is a SDH inhibitor, and shows inhibitory effect on nematode feeding, reproductive ability, and egg hatching. SDH-IN-11 promotes the oxidative stress of nematodes and causes intestinal damage to nematodes. SDH-IN-11 inhibits the activity of succinate dehydrogenase (SDH) in nematodes .
Synonyms: Dichlorophenylindophenol sodium (Standard); DCPIP sodium (Standard); Indochlorophenol sodium (Standard)
Cat. No.: HY-173264
Target:
Research Areas:
SDH-IN-24 (Compound 51) is an inhibitor of succinate dehydrogenase (SDH). The LC50 against the second-stage juveniles of Bursaphelenchus xylophilus (B. xylophilus) is 6.9 mg/L, and the IC50 for SDH is 15.0 μM. SDH-IN-24 exerts its nematicidal activity by inhibiting the activity of SDH to interfere with the energy metabolism of nematodes. Meanwhile, it inhibits the motility, feeding, and reproduction of nematodes, induces oxidative stress, reduces the protein content of nematodes, and impairs their antioxidant capacity. SDH-IN-24 can be used in the research related to anti-nematode fields .
Cat. No.: HY-119976S
CAS No.: 2468796-76-9
Cat. No.: HY-119976R
CAS No.: 188425-85-6
Cat. No.: HY-113298R
CAS No.: 498-23-7
Synonyms: Methylmaleic acid (Standard); Citraconate (Standard)
Research Areas:
Hydrolapachol is a mitochondrial respiratory chain inhibitor that targets the site between cytochrome b and c1, and inhibits succinate oxidation in rat liver mitochondria. Hydrolapachol can be used in studies related to mitochondrial respiration .
Cat. No.: HY-19688
CAS No.: 57695-04-2
Synonyms: WR 6026
Research Areas:
Sitamaquine (WR 6026) is an orally active Antileishmanial agent and Succinate dehydrogenase inhibitor. Sitamaquine accumulates in the acidocalcisomes of Leishmania, induces organelle alkalization, and crosses the plasma membrane of Leishmania via temperature- and energy-independent diffusion. Sitamaquine disrupts oxidative phosphorylation in Leishmania, induces mitochondrial depolarization, oxidative stress, elevated intracellular calcium, plasma membrane depolarization, and Apoptosis-like cell death. Sitamaquine can be used in the research of leishmaniasis .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
