2 Results for "

superhelical DNA

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "superhelical DNA" in MCE Product Catalog:

Cat. No.: HY-130050
CAS No.: 75580-37-9
Synonyms: BBM-928 A
Luzopeptin A (BBM-928 A) is an actinoleukin-like antitumor antibiotic. Luzopeptin A is a bifunctional DNA intercalator which can interact with isolated DNA molecules. Luzopeptin A induces an unwinding-rewinding process of the closed superhelical PM2 DNA. Luzopeptin A is active against HIV-1 and HIV-2 reverse transcriptase with IC50s of 7 nM and 68 nM for HIV-1 RT and HIV-2 RT, respectively .
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Cat. No.: HY-E71020
Research Areas:  

Metabolic Disease

Topoisomerase I, Human (EC 5.99.1.2) relaxes supercoiled DNA molecules. Topoisomerase I, Human (EC 5.99.1.2) initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA.
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