47 Results for "

synaptic vesicle

" in MedChemExpress (MCE) Product Catalog:
Products (47)

47 Results for "synaptic vesicle" in MCE Product Catalog:

15
Aminophylline
Aminophylline
0 Images
15 Publications Verification
Cat. No.: HY-B0140
CAS No.: 317-34-0
Category:  

Disease Research Fields Inflammation/Immunology

Target:  

Phosphodiesterase (PDE) Adenosine Receptor PPAR

Aminophylline is a competitive phosphodiesterase 3/4 (PDE3/4) inhibitor. Aminophylline also acts as an adenosine receptor antagonist. Aminophylline elevates intracellular cAMP levels via competitive inhibition of PDE3 and PDE4, antagonizes adenosine A1 receptor (ADORA1), regulates intracellular calcium signaling and synaptic vesicle cycling, upregulates the PPAR signaling pathway, and downregulates glutamatergic synaptic pathways simultaneously. Aminophylline can be used in research related to major depressive disorder, epilepsy, asthma, and chronic obstructive pulmonary disease (COPD) .
loading...
    loading...
View All Sizes
4
7-Chlorokynurenic acid
7-Chlorokynurenic acid
0 Images
4 Cited Publications
Cat. No.: HY-100811
CAS No.: 18000-24-3
Purity:  99.86%
Synonyms: 7-CKA
Target:  

iGluR

Research Areas:  

Neurological Disease

7-Chlorokynurenic acid (7-CKA) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid has potent antinociceptive actions after neuraxial delivery .
loading...
    loading...
View All Sizes
4
7-Chlorokynurenic acid sodium salt
7-Chlorokynurenic acid sodium salt
0 Images
4 Cited Publications
Cat. No.: HY-100811A
CAS No.: 1263094-00-3
Purity:  99.79%
Synonyms: 7-CKA sodium salt
Target:  

iGluR

Research Areas:  

Neurological Disease

7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) is a potent and selective antagonist of the glycine B coagonist site of the N-methyl-D-aspartate (NMDA) receptor (IC50=0.56 μM). 7-Chlorokynurenic acid sodium salt is also a potent inhibitor of the reuptake of glutamate into synaptic vesicles with a Ki of 0.59 μM. 7-Chlorokynurenic acid sodium salt has potent antinociceptive actions after neuraxial delivery .
loading...
    loading...
View All Sizes
3
Levetiracetam
Levetiracetam
0 Images
3 Cited Publications
Cat. No.: HY-B0106
CAS No.: 102767-28-2
Synonyms: UCB L059
Target:  

DNA Methyltransferase

Research Areas:  

Neurological Disease Cancer

Levetiracetam, an antiepileptic agent, binds the synaptic vesicle protein SV2A. Levetiracetam enhances Temozolomide effect on glioblastoma stem cell proliferation and apoptosis. Levetiracetam modulates HDAC levels ultimately silencing MGMT, thus increasing Temozolomide effectiveness. A chemosensitizer agent .
loading...
    loading...
View All Sizes
1
Tetrabenazine
Tetrabenazine
0 Images
1 Cited Publications
Cat. No.: HY-B0590
CAS No.: 58-46-8
Synonyms: Ro 1-9569
Target:  

Monoamine Transporter Dopamine Receptor

Research Areas:  

Neurological Disease

Tetrabenazine (Ro 1-9569) is a brain-penetrant and orally active VMAT2-selective ligand with human VMAT2 Ki 100 nM. Tetrabenazine binds VMAT2 to block monoamine uptake into synaptic vesicles, potentiates cytoplasmic monoamine degradation. Tetrabenazine weakly blocks dopamine D2 receptors, and increases dopamine turnover via elevated cerebrospinal fluid homovanillic acid. Tetrabenazine can be used for the research of Huntington’s disease, tardive dyskinesia, and Tourette’s syndrome .
loading...
    loading...
View All Sizes
1
Lobeline hydrochloride
Lobeline hydrochloride
0 Images
1 Cited Publications
Cat. No.: HY-B0979
CAS No.: 134-63-4
Synonyms: α-Lobeline hydrochloride; L-Lobeline hydrochloride
Category:  

Campanulaceae Extract Alkaloids Pyridine Alkaloids Plants 500 - Internal Server Error | MedChemExpress

Oops!

Sorry, Something went wrong on our server.
Our team has been notified and is working to fix the issue.