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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
14 Results for "
temperature stability
" in MedChemExpress (MCE) Product Catalog:
Products (14)
14 Results for "temperature stability" in MCE Product Catalog:
1
Category:
Ketones, Aldehydes, Acids Other Diseases Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields
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Cat. No.: HY-W099535
CAS No.: 2044-56-6
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Lithium dodecyl sulfate is an anionic hydrocarbon surfactant with both surface tension reduction and interfacial adsorption capabilities. Lithium dodecyl sulfate forms micelles in aqueous solutions via entropy-driven (low temperature) and enthalpy-driven (high temperature) mechanisms, and can also form an adsorption layer at the air-water interface with quantifiable surface excess and minimum area per molecule. Lithium dodecyl sulfate exhibits favorable equilibrium surface tension and foamability, but shows low foam stability above its critical micelle concentration. When acting synergistically with tetrabutylammonium bromide, Lithium dodecyl sulfate also exhibits unique cloud point behavior due to micelle aggregation and phase separation .
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DPhPC is a phospholipid compound characterized by high mechanical and chemical stability, broad temperature phase stability, and high electrical resistance. DPhPC readily forms unilamellar vesicles and solid-supported bilayers. DPhPC is commonly used as a component of nanoliposomal drug carriers or as a model membrane material for studies on membrane proteins/ion channels .
Cat. No.: HY-129047B
CAS No.: 9002-07-7
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Recombinant Trypsin Solution is an animal-free trypsin solution used to digest cells or tissues. Recombinant Trypsin Solution has high stability at room temperature and gentle digestion, and can be used to digest weakly adherent cells or stem cells under low serum or serum-free culture conditions. Compared with traditional trypsin digestion solution, Recombinant Trypsin Solution does not contain any animal-derived ingredients, is gentle and effective, and can replace the application of animal-derived trypsin in cell digestion .
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Hexokinase, microorganism is a hexokinase derived from microorganisms. It catalyzes the phosphorylation of glucose at the C6 position using ATP and Mg 2+, exhibits broad substrate specificity, and demonstrates thermal stability under neutral to weakly alkaline pH and high-temperature conditions. Hexokinase, microorganism uses ATP as the primary phosphate donor for sugar phosphorylation reactions. Hexokinase, microorganism belongs to the prokaryotic hexokinase family and catalyzes sugar phosphorylation reactions in carbohydrate metabolism .
Cat. No.: HY-E70318
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Penicillin G acylase (Immobilized) is an immobilized penicillin acylase with improved temperature and pH stability. Penicillin G acylase (Immobilized) has reusable performance and high recovery rates, retaining much of its original activity after 12 cycles. Among them, Penicillin G acylase (Immobilized) can catalyze penicillin G (PG) to generate 6-aminopenicillanic acid (6-APA) and 7-aminodeacetoxycephalosporanic acid, which are key intermediates for β-lactam antibiotics .
Cat. No.: HY-125209A
CAS No.: 2253744-57-7
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TH5427 hydrochloride is a NUDT5 inhibitor with a human target IC50 of 29 nM, ~690-fold selectivity over MTH1 in vitro, and selective functional inhibition over other NUDIX hydrolases including NUDT9 .TH5427 hydrochloride binds to the active site of NUDT5, blocking enzymatic activity related to ADP-ribose metabolism and PAR-derived ATP synthesis .TH5427 hydrochloride blocks progestin-dependent nuclear ATP synthesis, impairs progestin-induced chromatin remodeling, inhibits histone H1 displacement, disrupts progestin-dependent gene regulation, and abrogates progestin-dependent proliferation in breast cancer cells .TH5427 hydrochloride functions as a versatile probe to study nuclear ATP dynamics and ADP-ribose-related metabolism in cells .TH5427 hydrochloride engages NUDT5 at physiological temperatures, as demonstrated by Drug Affinity Responsive Target Stability (DARTS) assay .TH5427 hydrochloride stabilizes NUDT5 against thermal denaturation in cell lysates and intact cells, as shown by cellular thermal shift assay (CETSA) .TH5427 hydrochloride functionally inhibits NUDT5 activity, leading to downstream effects on oxidative DNA damage and DNA replication in triple-negative breast cancer (TNBC) cells .TH5427 hydrochloride suppresses proliferation of TNBC cells without inducing cell death or apoptosis, slows DNA replication in TNBC cells, promotes accumulation of oxidative DNA lesions, and triggers DNA damage response in TNBC cells .TH5427 hydrochloride suppresses growth of TNBC cells in vitro, inhibits growth of TNBC xenograft tumors in nude mice in vivo, and shows greater potency against TNBC cell lines compared to ER-positive and normal-like breast cell lines .TH5427 hydrochloride can be used for the research of breast cancer and triple-negative breast cancer .
Cat. No.: HY-W014130R
CAS No.: 155-84-0
Synonyms: Ac-Arg-OH (Standard)
Cat. No.: HY-E70124B
CAS No.: 9013-79-0
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Esterase, Bacillus stearothermophilus is a carboxylate hydrolase. Esterase, Bacillus stearothermophilus has a higher temperature stability .
Cat. No.: HY-P11171
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Cat. No.: HY-143202S
Cat. No.: HY-143202S1
CAS No.: 1638338-77-8
Cat. No.: HY-184756
CAS No.: 25212-74-2
Synonyms: Polyphenylene sulfide; PPS
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Poly (1,4-phenylene sulfide) (Polyphenylene sulfide; PPS) is a semicrystalline high-performance engineering plastic and also a thermoplastic aromatic sulfide polymer, which possesses multiple properties including high temperature stability, flame retardancy, chemical resistance, favorable mechanical and electrical properties, and inertness to singlet oxygen. Poly (1,4-phenylene sulfide) can be applied to relevant research in fields such as machinery and industrial manufacturing .
Cat. No.: HY-117387
CAS No.: 107572-73-6
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BFE-37 is a yeast introduction with heat resistance activity. The survival rate change of BFE-37 after heating at 55 °C for 5 minutes was 6.53 log CFU/mL, showing its strong heat resistance in acidic orange juice. The dynamic behavior of BFE-37 at different temperatures showed a first-order logarithmic linear inactivation characteristic, which indicates its stability in heat treatment. The study of BFE-37 helps to understand the effect of mild heat treatment on juice and provide guidance for microbial control in the food industry .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
