Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
26 Results for "
thiol protease
" in MedChemExpress (MCE) Product Catalog:
Products (26)
26 Results for "thiol protease" in MCE Product Catalog:
168
168 Cited Publications
Synonyms: Phenylmethylsulfonyl fluoride; Benzylsulfonyl fluoride
Target:
Research Areas:
PMSF (Phenylmethylsulfonyl fluoride) is a nonspecific and irreversible serine proteases inhibitor. PMSF inhibits some thiol proteases, non-protease enzymes, and acetylcholinesterase. PMSF can be used to prepare protein extracts from tissue and cell lysates .
2
2 Cited Publications
Cat. No.: HY-15941
CAS No.: 27072-45-3
Synonyms: Fluorescein 5(6)-isothiocyanate; Fluorescein isothiocyanate 5- and 6- isomers
Target:
Research Areas:
Clostripain (Clostridiopeptidase B) is a thiol protease isolated from Clostridium histolyticum. Clostripain exhibits proteolytic activity as well as amidase-esterase activity. The specificity of Clostripain is primarily restricted to arginine residues, but it also shows minor hydrolytic activity toward most lysine-containing substrates. Clostripain catalyzes the ammonolysis of Carbobenzoxyarginyl methyl ester to generate various dipeptides .
Cat. No.: HY-E70364
CAS No.: 1892548-76-3
Target:
Research Areas:
IgdE protease is a cysteine protease, which is initially isolated from Streptococcus agalactiae. IgdE protease digests monoclonal antibodies (mAbs) of the IgG1 type specifically at their upper hinge region, produces Fc/2, hinge peptide dimers, and Fab fragment. IgdE protease can be used in disulfide bonds and free thiol analysis, as it requires no reducing agents for cleavage .
Cat. No.: HY-P10828
CAS No.: 1260620-30-1
Target:
Research Areas:
Cat. No.: HY-N14193
CAS No.: 106396-24-1
Category:
Target:
Cat. No.: HY-120288
CAS No.: 160825-49-0
Target:
Research Areas:
AM4299B is an inhibitor for thiol protease. AM4299B inhibits bovine spleen cathepsin B, human kidney cathepsin L and papain with IC50s of 0.7, 0.5 and 20 μM, respectively. AM4299B can be used in research in osteoporosis, and has potential to be used as an antiparasitic agent .
Cat. No.: HY-152919
CAS No.: 2387738-43-2
Target:
Research Areas:
Mal-amide-PEG8-Val-Cit-PAB-OH is a cleavable ADC linker featuring a maleimide, a hydrophilic PEG spacer, a Val-Cit dipeptide, and a PAB functional group. Maleimide is used to covalently bind free thiols on the cysteine residues of proteins. The Val-Cit dipeptide is cleaved by cellular proteases within the cell to allow for efficient payload delivery with the help of the PAB structure.
Cat. No.: HY-P703536
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:
Virus
Source:
E. coli
Cat. No.: HY-P703539
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:
Virus
Source:
E. coli
Cat. No.: HY-P703534
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:
Virus
Source:
E. coli
Cat. No.: HY-P703535
Purity: ≥ 80%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:
Virus
Source:
E. coli
Cat. No.: HY-P703537
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:
Virus
Source:
E. coli
Cat. No.: HY-P703538
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Replicase polyprotein 1a; ORF1a polyprotein; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1a; Endonuclease; Hydrolase; Methyltransferase; Nuclease; protease; RNA-binding; thiol protease; Transferase
Species:
Virus
Source:
E. coli
Cat. No.: HY-P703543
Synonyms: Replicase polyprotein 1ab; ORF1ab polyprotein; rep; Severe acute respiratory syndrome coronavirus 2; 2019-nCoV; pp1ab; Endonuclease; Exonuclease; Helicase; Hydrolase; Lyase; Methyltransferase; Nuclease Nucleotidyltransferase; protease; RNA-binding; RNA-directed RNA polymerase; thiol protease; Transferase;
Species:
Virus
Source:
Sf9 insect cells
Cat. No.: HY-187615
CAS No.: 160825-48-9
Target:
Research Areas:
AM4299 A is a thiol protease inhibitor with IC50 values of 73, 390 and 88 nM against Cathepsin B, Cathepsin L and Papain, respectively. AM4299 A shows low toxicity and favorable biosafety in mice. AM4299 A can be used in studies related to osteoporosis and parasitic diseases .
Cat. No.: HY-E70958
Target:
Research Areas:
Carboxypeptidase G, Pseudomonas sp. (EC 3.4.17.11) is a lysosomal thiol-dependent protease that stepwise cleaves γ-glutamylpteroyl polyγ-glutamic acid to generate pteroyl-α-glutamic acid (folic acid) and free glutamic acid. Carboxypeptidase G is highly specific for the γ-glutamyl bond but not for the C-terminal amino acid of the leaving group. Carboxypeptidase G can be activated by Zn 2+ ions.
Cat. No.: HY-P703430
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ulp1; SPBC19G7.09; Ubiquitin-like-specific protease 1; EC 3.4.22.-
Species:
Others
Source:
E. coli
Cat. No.: HY-P703433
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: Sortase A; EC:3.4.22.70; Surface protein sorting A; srtA; SAOUHSC_02834
Species:
Others
Source:
E. coli
- 1
- 2
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
