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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
117 Results for "
thiol reaction
" in MedChemExpress (MCE) Product Catalog:
Products (117)
117 Results for "thiol reaction" in MCE Product Catalog:
25
25 Publications Verification
Cat. No.: HY-W011500
CAS No.: 51805-45-9
Synonyms: Tris(2-carboxyethyl)phosphine hydrochloride
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TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol reducing agent that is more stable and produces a faster S-S reductive reaction than other chemical reductants. TCEP hydrochloride is a trialkylphosphine, selectively reduces protein disuldes without altering the properties or interacting with thiol-directed agents in the reaction mixture. TCEP hydrochloride is also a commonly used reducing agent in the DNA/AuNP chemistry .
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6 Cited Publications
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RT-AM is a pro-agent real thiol. Real Thiol is a reversible reaction-based fluorescent probe which can quantitatively monitor the real-time glutathione dynamics in living cells.
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3 Cited Publications
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N-Acetyl-D-cysteine has antioxidant activities and scavenges ROS through the reaction with its thiol group, but cannot enter the glutathione metabolic pathway .
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1
1 Cited Publications
Cat. No.: HY-W011500S
CAS No.: 1174025-33-2
Cat. No.: HY-W068119A
CAS No.: 134272-64-3
Synonyms: 2-Maleimidoethylamine hydrochloride
Cat. No.: HY-138525
CAS No.: 2720615-82-5
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Azido-PEG4-Thiol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . Azido-PEG4-Thiol is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
Cat. No.: HY-107783
CAS No.: 185332-92-7
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Sulfo-GMBS is a crosslinker widely used in chemical modification and coupling reactions of proteins and peptides. Among amine-thiol crosslinkers, Sulfo-GMBS generates the largest number of crosslinks and covers most of the crosslinks identified by AMAS and GMBS .
Cat. No.: HY-D1590
CAS No.: 929679-22-1
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ODIPY Green 8-P2M is a novel thiol-reactive fluorescence probe based on the BODIPY fluorophore, the fluorescence is strongly quenched by d-PeT and then can be restored after reaction with thiol, resulting in an extremely high signal-to-noise ratio. ODIPY Green 8-P2M can be useful for detecting extremely low concentrations of protein in the gel after SDS-PAGE .
Cat. No.: HY-174965C
Synonyms: DBCO-PEG-thiol (MW 2000)
Cat. No.: HY-D1262
CAS No.: 1808174-52-8
Synonyms: thiol-green 2
Cat. No.: HY-W591476B
CAS No.: 134874-49-0
Synonyms: mPEG750-SH
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Poly (ethylene glycol) dithiol (Mn 3400) is a bifunctional thiol-terminated PEG crosslinking and polymerization reagent. The terminal thiol groups of Poly (ethylene glycol) dithiol (Mn 3400) can undergo thiol-ene photochemical click reactions with norbornene groups, thereby crosslinking to form hydrogel networks; it can also serve as a dithiol monomer in the step-growth polymerization of hexahydrotriazine (HT) to form poly (thioaminal) polymers containing dynamic thioacetal bonds. Poly (ethylene glycol) dithiol (Mn 3400) is applicable for hydrogel construction, biomanufacturing, and dynamic covalent polymer research .
Cat. No.: HY-W872575
CAS No.: 1914971-04-2
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TCO4-PEG3-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG3-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
Cat. No.: HY-W019828
CAS No.: 762-72-1
Synonyms: Trimethyl-prop-2-enylsilane
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Allyltrimethylsilane (Trimethyl-prop-2-enylsilane) is an organosilicon compound. Allyltrimethylsilane undergoes photochemical thiol-ene reactions with thiolated soybean oil. Allyltrimethylsilane participates in carbon-carbon bond formation via allylation reactions with acetals, ketals, aldehydes and ketones, forms cyclopropane through reaction with aldehydes, and reacts with iodine to produce trimethylsilyl iodide. Allyltrimethylsilane is applicable to research related to organic synthesis .
Synonyms: AMD473; ZD0473
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Picoplatin (AMD473) is a platinum-based antineoplastic agent. Picoplatin is specifically to circumvent thiol-mediated drug resistance by sterically hindering its reaction with glutathione (GSH) while still retaining the ability to form cytotoxic lesions with DNA .
Cat. No.: HY-W002465
CAS No.: 5570-19-4
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2-Nitrophenylboronic acid is a small-molecule arylboronic acid reagent selective for cysteine residues that mediates nickel (II)-promoted arylation of cysteine thiols. 2-Nitrophenylboronic acid is used in research related to peptide modification and also serves as a substrate for Suzuki-Miyaura coupling reactions in research related to organic synthesis .
Cat. No.: HY-156392
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TCO4-PEG7-Maleimide is a PROTAC linker and belongs to the PEG class. TCO4-PEG7-Maleimide contains TCO and Maleimide groups, which can undergo specific "click" reactions with tetrazine groups or thiol groups, or "mercapto-acrylamide" reactions.
Cat. No.: HY-E70264
CAS No.: 799812-86-5
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16:0 Coenzyme A triammonium is palmitoyl-CoA, which can serve as a reaction substrate to transfer the palmitoyl group to the free thiol group of the target protein through palmitoylation catalyzed by protein acyl transferases (PATs) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
