2 Results for "

threshold pressure

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "threshold pressure" in MCE Product Catalog:

Cat. No.: HY-120496
CAS No.: 1204178-50-6
Synonyms: ASP3662
Target:  

11β-HSD

Clofutriben (ASP3662) is a selective, orally active and brain-penetrant 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with Ki values of 5.3 nM (human), 2.6 nM (mouse), and 23 nM (rat). Clofutriben inhibits conversion of inactive glucocorticoids to active glucocorticoids, reducing intracellular glucocorticoid exposure. Clofutriben ameliorates neuropathic pain, and restores muscle pressure thresholds in rodent models, while lacking effects in inflammatory pain .
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Cat. No.: HY-W277805
CAS No.: 549-68-8
Category:  

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