52 Results for "

tracheal

" in MedChemExpress (MCE) Product Catalog:
Products (52)

52 Results for "tracheal" in MCE Product Catalog:

16
TAPI-1
TAPI-1
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16 Publications Verification
Cat. No.: HY-16657
CAS No.: 163847-77-6
Target:  

MMP NF-κB Apoptosis TNF Receptor

Research Areas:  

Inflammation/Immunology Cancer

TAPI-1 is a broad-spectrum MMP inhibitor and NF-κB p65 inhibitor that targets ADAM17/TACE, ADAM10 and other proteins. TAPI-1 reduces the proteolytic cleavage of membrane-bound TNF-α, decreases TNF-α levels, inhibits NF-κB pathway activation, and downregulates profibrotic markers. TAPI-1 reduces the proportion of proinflammatory immune cells, alleviates cardiac and airway fibrosis, and improves cardiac function after myocardial infarction. Meanwhile, TAPI-1 inhibits the viability, migration and invasion of esophageal squamous cell carcinoma cells, enhances the chemosensitivity of Cisplatin (HY-17394), induces apoptosis, and shows low toxicity to normal esophageal epithelial cells. TAPI-1 can be widely used in studies related to myocardial infarction-induced heart failure, severe traumatic tracheal stenosis, esophageal squamous cell carcinoma and other conditions .
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11
Ibudilast
Ibudilast
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11 Cited Publications
Cat. No.: HY-B0763
CAS No.: 50847-11-5
Synonyms: KC-404; AV-411; MN-166
Target:  

Phosphodiesterase (PDE)

Research Areas:  

Inflammation/Immunology Cancer

Ibudilast (KC-404; AV-411; MN-166) is a cyclic AMP phosphodiesterase (PDE) inhibitor. Ibudilast has platelet anti-aggregatory effects. Ibudilast can be used for the research of asthma for its inhibitory effects on tracheal smooth muscle contractility. Ibudilast may be a useful neuroprotective and anti-dementia agent counteracting neurotoxicity in activated microglia .
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1
JNJ-7777120
JNJ-7777120
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1 Cited Publications
Cat. No.: HY-13508
CAS No.: 459168-41-3
Purity:  99.95%
Target:  

Histamine Receptor

Research Areas:  

Inflammation/Immunology

JNJ-7777120 is a potent and selective histamine H4 receptor antagonist (Ki=4.5 nM). JNJ-7777120 effectively blocks histamine-induced migration of mouse tracheal mast cells from connective tissue to epithelial cells. JNJ-7777120 also significantly blocks neutrophil infiltration in a mouse Zymosan-induced peritonitis model. JNJ-7777120 has a good potential to study antipruritic and anti-inflammatory .
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Marmin
Marmin
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Cat. No.: HY-N3320
CAS No.: 14957-38-1
Category:  

Rutaceae Extract Coumarins Phenylpropanoids Plants 500 - Internal Server Error | MedChemExpress

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