2 Results for "

transcellular passive diffusion

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "transcellular passive diffusion" in MCE Product Catalog:

Cat. No.: HY-167702
CAS No.: 81397-67-3
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

(Rac)-Acetoxyvalerenic acid is a derivative of valerenic acid that acts as a GABA (A) receptor modulator, potentially providing sedative and sleep-enhancing effects. (Rac)-Acetoxyvalerenic acid exhibits slower permeability across the blood-brain barrier compared to diazepam, indicating that its transport may rely on an unidentified pathway rather than transcellular passive diffusion.
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Cat. No.: HY-N18411
CAS No.: 1401-54-3
Tanacetin is a sesquiterpenoid compound discovered in the whole herb of Crossostephium chinense (L.) Makino. Sesquiterpene lactones, the class to which Tanacetin belongs (e.g., constituents of plants in the Tanacetum genus), inhibit the inflammatory mediators prostaglandins and leukotrienes. Tanacetin crosses intestinal cell monolayers primarily via transcellular passive diffusion, and no significant first-pass metabolism occurs during its intestinal absorption. Tanacetin is used in research related to diabetes, migraine, and rheumatoid arthritis .
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