90 Results for "

transferrin receptor

" in MedChemExpress (MCE) Product Catalog:
Products (90)

90 Results for "transferrin receptor" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-P3267
CAS No.: 11096-37-0
Holo-Bovine Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Holo-Bovine Transferrin can bind to and mediate the transport of iron .
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2
2 Cited Publications
Cat. No.: HY-107928
CAS No.: 9004-66-4
Synonyms: Fe dextran
Target:  

Transferrin Receptor

Research Areas:  

Metabolic Disease Cancer

Iron dextran (Fe dextran) can be used in the study of iron-deficiency anemia in animals .
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1
1 Cited Publications
Cat. No.: HY-159569
CAS No.: 1643444-62-5
Research Areas:  

Cancer

TfR-1-IN-1 is a transferrin receptor-1 (TfR-1) inhibitor with tumor cell-specific activity. TfR-1-IN-1 reduces TfR-1 expression, impairs mitochondrial function, induces cell apoptosis, necroptosis and ferroptosis, and increases intracellular iron (II) levels. TfR-1-IN-1 decreases the metabolic activity of cancer cells. TfR-1-IN-1 can be used for the research of ovarian cancer, breast cancer and acute myeloid leukemia .
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1
1 Cited Publications
Cat. No.: HY-P71069
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: TFRC; transferrin receptor (P90, CD71); transferrin receptor; CD71 Antigen; P90; IMD46; transferrin receptor Protein 1; TRFR; CD71; Trfr; TFR1; TfR1; transferrin receptor 1; TFR; T9; TfR; TR
Species:  
Human
Source:  
HEK293
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Cat. No.: HY-P9999
CAS No.: 2568868-35-7
Synonyms: RG6102; RO-7126209

Target:  

Amyloid-β

Research Areas:  

Neurological Disease

Trontinemab (RG6102) is a brain-penetrant, anti-amyloid, bispecific and humanizedized IgG1-κ antibody, targeting to Aβ plaques and transferrin receptor 1 (TFR1). Trontinemab binds to fibrillar Aβ as well as Aβ plaques triggering plaque clearance by engaging immune cells on Alzheimer disease (AD) brain sections. Trontinemab also shows specific affinity to cynomolgus and human TFR1 .
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Cat. No.: HY-P991047
Synonyms: JR-141 antibody (uncoupled from iduronate 2-sulfatase)

Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease Cancer

Anti-CD71/TfR1 Antibody (JR-141 antibody (uncoupled from iduronate 2-sulfatase)) is a humanized anti-human transferrin receptor (CD71/TfR1) antibody. Anti-CD71/TfR1 Antibody is the antibody part of the fusion protein Pabinafusp alfa (HY-P99797). The recommend isotype control of Anti-CD71/TfR1 Antibody: Human IgG1 kappa, Isotype Control (HY-P99001) .
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Cat. No.: HY-P990051
CAS No.: 2653183-66-3
Synonyms: AOC-1001 Antibody; AOC-1044 Antibody
Delpacibart is a humanized IgG1κ monoclonal antibody targeting the transferrin receptor TFRC. Delpacibart can be conjugated with the phosphorodiamidate morpholino oligonucleotide (PMO) Zotadirsen (HY-177972), which targets exon 44 of the dystrophin gene, to synthesize the antibody-oligonucleotide conjugate (AOC) Delpacibart zotadirsen (HY-177564). Delpacibart is suitable for use in Duchenne muscular dystrophy (DMD44) research .
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Cat. No.: HY-P99797
CAS No.: 2140211-48-7
Synonyms: JR-141

Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease

Pabinafusp alfa (JR-141) is a transferrin receptor-targeting antibody consisting of Iduronate 2-sulfatase (HY-P76399) and an anti-human transferrin receptor antibody. Pabinafusp alfa is blood-brain permeable and prevents heparan sulfate (HS) deposition in the central nervous system of mucopolysaccharidosis II (MPS II) mice. Pabinafusp alfa improves learning and prevents central nervous system neuronal damage in mice .
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Cat. No.: HY-B1651
CAS No.: 141-01-5
Synonyms: Ferrous fumarate
Target:  

Transferrin Receptor

Research Areas:  

Metabolic Disease Cancer

Iron (II) fumarate is an orally effective active dietary supplement. Iron (II) fumarate can alleviate metabolic damage and damage to silkworms caused by cypermethrin (HY-123178). Iron (II) fumarate can be used for research on iron deficiency anemia .
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Cat. No.: HY-172723
Research Areas:  

Neurological Disease Cancer

DSPE-PEG2000-T7 is a PEGylated compound composed of DSPE and peptideT7. T7 (HAIYPRH) specifically binds to TfR. DSPE-PEG2000-T7 can be used to prepare T7-modified liposomes, where liposomes modified with both T7 and DA7R peptides can effectively co-deliver Doxorubicin (HY-15142A) and Vincristine (HY-N0488A) to gliomas. DSPE-PEG2000-T7 can also be used to prepare nanomodulators that mediate the co-delivery of tyrosine hydroxylase mRNA and interferon gene stimulator antagonists for synergistic intervention in Parkinson's disease .
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Cat. No.: HY-P3267A
CAS No.: 11096-37-0
Apo-Bovine Transferrin refers to iron free Transferrin (HY-P3267), serves as Transferrin receptor ligand and mediates iron release from endothelial cells. Apo-Transferrin can directly bind to hephaestin, which can convert Fe 2+ to Fe 3+. Apo-Transferrin mediates iron efflux most likely in cooperation with ferroportin 1. Apo-Bovine Transferrin can be used in neuroretinal research .
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Cat. No.: HY-P2297
CAS No.: 344618-30-0
Target:  

Transferrin Receptor

Research Areas:  

Metabolic Disease

TfR-T12 is a BBB-penetrated transferrin receptor (TfR) binding peptide, displaying a binding affinity in the nM range .
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Cat. No.: HY-130078
CAS No.: 20150-34-9
Purity:  ≥98.0%
Ferrous bisglycinate is an orally active iron fortificants and therapeutic iron supplements. Ferrous bisglycinate can be used for the research of iron deficiency anemia .
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Cat. No.: HY-P11099
CAS No.: 1254540-73-2
Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease Cancer

Cys-LT7 is a transferrin receptor (TfR)-targeting peptide ligand. Cys-LT7 binds to a TfR site distinct from endogenous transferrin, mediates conjugated Doxorubicin (HY-15142A) delivery to TfR-overexpressed tumor cells, and exhibits low toxicity to TfR-low-expressed normal cells. Cys-LT7 is an L-configuration peptide susceptible to proteolytic enzymes, leading to poor biostability in peptide-drug conjugates. Cys-LT7 can be used for the research of glioblastoma, hepatocellular carcinoma, lung carcinoma .
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Cat. No.: HY-D2426
Cy3-Transferrin is a fluorescent labeling reagent that combines Cy3 (HY-D0822) fluorescent dye and Transferrin (HY-P3267). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. Transferrin, a blood-plasma glycoprotein, is a target ligand for transferrin receptor. Transferrin can bind to and mediate the transport of iron .
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Cat. No.: HY-P2314
Target:  

Transferrin Receptor

Research Areas:  

Cancer

HAIYPRH hydrochloride, a targeting ligand, can specially bind to transferrin receptor (TfR). HAIYPRH hydrochloride can mediate the transport of nanocarriers across the blood-brain barrier .
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Cat. No.: HY-P990129

Target:  

Transferrin Receptor

Research Areas:  

Infection

Anti-Mouse CD71/TfR1 Antibody (8D3) is a rat-derived anti-mouse CD71/TfR1 IgG2a type antibody inhibitor. Anti-Mouse CD71/TfR1 Antibody (8D3) depletes of CD71+ erythroid cells but does not change percentages of Tregs in neonatal mice. Anti-Mouse CD71/TfR1 Antibody (8D3) enhances neonatal mice defence against infection .
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Cat. No.: HY-P991381
Synonyms: PPMX-T003; TSP-A18
JST‑TfR09 (PPMX‑T003) is a human monoclonal antibody (mAb) targeting transferrin receptor 1 (TfR1/CD71). JST‑TfR09 blocks the binding of transferrin to TfR1, inhibits TfR1 internalization, and suppresses cellular iron uptake. JST‑TfR09 triggers ferritin degradation via activating the autolysosomal system, promotes ROS production and lipid peroxidation, and ultimately induces ferroptosis. JST‑TfR09 exhibits cytotoxicity toward human erythroblasts differentiated from hematopoietic stem cells. JST-TfR09 can be used in leukemia research. Recommended isotype control: Human IgG1 lambda, Isotype Control (HY-P99992) .
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Cat. No.: HY-P990130

Target:  

Transferrin Receptor

Research Areas:  

Neurological Disease

Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26) is a mouse-derived IgG2a κ type antibody, targeting to mouse/rat CD71/TfR1. Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26) targets the transferrin receptor and binds to an extracellular domain for the transferrin receptor. Anti-Mouse/Rat CD71/TfR1 Antibody (OX-26) can be used for the research in drug delivery, especially for drug delivery to the brain .
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Cat. No.: HY-P990856

Target:  

Transferrin Receptor

Research Areas:  

Cancer

Anti-CD71 Antibody (OKT-9) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD71. Anti-CD71 Antibody (OKT-9) can recognize CD71 also known as Transferrin receptor protein 1 (TfR1). Anti-CD71 Antibody (OKT-9) can be used for the detections of immunohistochemistry, immunofluorescence and flow cytometry in cancer, such as leukemia and lymphoma .
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