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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
71 Results for "
twisted nanotubes
" in MedChemExpress (MCE) Product Catalog:
Products (71)
71 Results for "twisted nanotubes" in MCE Product Catalog:
629
629 Publications Verification
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Y-27632 is a ROCK inhibitor with Ki values of 220 nM and 300 nM for ROCK1 and ROCK2, respectively. Y-27632 exerts anti-inflammatory and immunomodulatory effects in systemic lupus erythematosus models by inhibiting the ROCK/NF-κB pathway. Y-27632 enhances autophagy by inhibiting the AKT/mTOR pathway, thereby inducing apoptosis apoptosis in oral squamous cell carcinoma. Y-27632 induces the formation of tunneling nanotubes in ARPE-19 cells and significantly enhances mitochondrial transfer through these channels. Y-27632 promotes neurite outgrowth in PC12 cells by activating the Rac1/NOX1/ROS/AKT/PAK1 signaling cascade .
629
629 Publications Verification
Cat. No.: HY-10071A
CAS No.: 331752-47-7
Research Areas:
Y-27632 hydrochloride hydrate is a ROCK inhibitor with Ki values of 220 nM and 300 nM for ROCK1 and ROCK2, respectively. Y-27632 hydrochloride hydrate exerts anti-inflammatory and immunomodulatory effects in systemic lupus erythematosus models by inhibiting the ROCK/NF-κB pathway. Y-27632 hydrochloride hydrate enhances autophagy by inhibiting the AKT/mTOR pathway, thereby inducing apoptosis apoptosis in oral squamous cell carcinoma. Y-27632 hydrochloride hydrate induces the formation of tunneling nanotubes in ARPE-19 cells and significantly enhances mitochondrial transfer through these channels. Y-27632 hydrochloride hydrate promotes neurite outgrowth in PC12 cells by activating the Rac1/NOX1/ROS/AKT/PAK1 signaling cascade .
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1 Cited Publications
Cat. No.: HY-Y0395
CAS No.: 25487-66-5
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Human Serum Albumin-FITC (HSA-FITC) is a green fluorescent probe prepared by covalent conjugation of FITC with human serum albumin (HSA), with excitation/emission wavelengths of 488/505-550 nm. Human Serum Albumin-FITC (HSA-FITC) can be used to track nanotube conjugates taken up via caveolae-mediated endocytosis initiated by Gp60 receptor binding, and can also non-covalently adsorb to oxidized multi-walled carbon nanotubes. Human Serum Albumin-FITC (HSA-FITC) is widely applied in macrophage imaging, scavenger receptor targeting, and hepatoma cell imaging .
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BETA-1 is the first twisted intramolecular charge transfer (TICT)-aggregation-induced emission (AIE) integration molecule. BETA-1 emits cyan fluorescence in lipid droplets (LDs) and red fluorescence in mitochondria. BETA-1 can be used for the simultaneous and dual-color imaging of LDs and mitochondria in vivo and in vitro .
Cat. No.: HY-W284558
CAS No.: 1120-01-0
Cat. No.: HY-N16025
CAS No.: 2342575-85-1
Synonyms: DOPE-PEG2000-NH2 ammonium
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DOPE-PEG2000-Amine (DOPE-PEG2000-NH2) ammonium is a polyethylene glycol-derivatized phospholipid that can be used to construct liposomes and lipid nanoparticles. DOPE-PEG-Amine ammonium is used for non-covalent functionalization of single-walled carbon nanotubes (SWCNTs) to enhance their water dispersibility and biocompatibility. DOPE-PEG-Amine ammonium can be applied in research related to photothermal applications .
Cat. No.: HY-W541025
CAS No.: 9007-49-2
Cat. No.: HY-D1138
CAS No.: 61951-82-4
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TR-100 is a Tpm3.1 inhibitor that binds to and disrupts Tpm3.1-containing Actin filaments, enhancing the depolymerizing effect of Tpm3.1 on actin without altering actin-tropomyosin binding. TR-100 induces actin cytoskeleton rearrangement. TR-100 shortens membrane nanotubes and alters tube thickness in a concentration-dependent manner. TR-100 increases basal insulin secretion and inhibits glucose-stimulated insulin secretion. TR-100 inhibits insulin-stimulated glucose uptake. TR-100 can be used for research on B lymphoma .
Cat. No.: HY-160052
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IL-6 aptamer sodium is an aptamer that specifically binds to IL-6, and can serve as a biological recognition receptor for high-sensitivity detection. IL-6 aptamer sodium enables label-free specific detection through changes in electrical signals of carbon nanotube microarrays or alterations in capacitive impedance on the surface of gold sensors. IL-6 aptamer sodium still maintains high selectivity even below the gray zone threshold for cancer diagnosis, and shows no significant non-specific binding to bovine serum albumin. IL-6 aptamer sodium can form an ordered self-assembled monolayer with 6-mercapto-1-hexanol on gold surfaces, making it suitable for reagent-free capacitive impedance biosensing platforms. IL-6 aptamer sodium is widely used in research related to fields such as cancer, inflammatory diseases, myeloma, liver cancer and glioma .
Cat. No.: HY-N8624
CAS No.: 143051-73-4
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Gynura divaricata (Linn.) DC. Extract Plant Phenols Polyphenols Compositae/Asteraceae Extract
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Cat. No.: HY-P11501
CAS No.: 1038400-67-7
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Cat. No.: HY-D2317
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HaloFlipper 30 is a fluorescent HaloTag fusion protein probe. HaloFlipper 30 reacts with aspartate residues via a terminal chloroalkane to form an ester bond, achieving covalent attachment and membrane insertion; its ethylene glycol linker allows cell penetration, and genetic engineering of the HaloTag fusion protein enables intracellular targeting and labeling of membranes such as the ER, Golgi, and cytoplasm. HaloFlipper 30 enables mechanosensitive membrane tension imaging through planarization of a twisted push-pull mechanoresponsive group in the ground state .
Cat. No.: HY-B1306S
CAS No.: 1219805-41-0
Synonyms: p-Aminohippuric acid-d4
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
