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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
urethral closure
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "urethral closure" in MCE Product Catalog:
Cat. No.: HY-14790
CAS No.: 98819-76-2
Synonyms: (S,S)-(+)-Reboxetine
Target:
Esreboxetine ((S,S)-Reboxetine) is a selective norepinephrine transporter (NET) inhibitor, with a pIC50 of 9.6 and a pKi of 9.2 in rats, and it can cross the blood-brain barrier. Esreboxetine increases urethral closure pressure and urethral resistance in rats. Esreboxetine is applicable to research related to inflammatory pain and stress urinary incontinence .
Cat. No.: HY-167677
CAS No.: 1334440-09-3
Target:
Research Areas:
ASP-2205 is a 5-HT2C receptor agonist (human 5-HT2C receptor, EC50=0.85 nM; rat 5-HT2C receptor, EC50=2.5 nM). ASP-2205 enhances the pudendal nerve-mediated urethral closure reflex through the 5-HT2C receptor, thereby preventing urinary incontinence .
Cat. No.: HY-14790A
CAS No.: 635724-55-9
Synonyms: PNU-165442G; (S,S)-Reboxetine succinate
Target:
Research Areas:
Esreboxetine succinate (PNU-165442G; (S,S)-Reboxetine succinate) is a selective norepinephrine transporter (NET) inhibitor, with a pIC50 of 9.6 and a pKi of 9.2 in rats, and it can cross the blood-brain barrier. Esreboxetine succinate increases urethral closure pressure and urethral resistance in rats. Esreboxetine succinate is applicable to research related to inflammatory pain and stress urinary incontinence .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
