Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
11 Results for "
vasculitis
" in MedChemExpress (MCE) Product Catalog:
Products (11)
11 Results for "vasculitis" in MCE Product Catalog:
Target:
Research Areas:
PAD-IN-2 is a potent pad4 inhibitor (IC50: <1 μM). PAD-IN-2 can be used in the research of auto-immune diseases and cancers, such as rheumatoid arthritis, vasculitis, systemic lupus erythematosis, cutaneous lupus erythematosis, ulcerative colitis, cystic fibrosis, asthma, multiple sclerosis and psoriasis .
Cat. No.: HY-P991538
Target:
Research Areas:
VIS954 is an anti-C5a anaphylatoxin chemotactic receptor 1 (C5AR1) monoclonal antibody. VIS954 can be studied in research for anti-neutrophil cytoplasmic antibody-associated vasculitis (ANCA Vasculitis) and IgA nephrophathy .
Cat. No.: HY-115676
CAS No.: 2048226-46-4
Target:
Research Areas:
GSK199 analog hydrochloride belongs to a class of compounds that inhibit PAD4 (guanidinoarginine deiminase 4). GSK199 analog hydrochloride has potential uses in diseases including rheumatoid arthritis, vasculitis, systemic lupus erythematosus, ulcerative colitis, cancer, cystic fibrosis, asthma, cutaneous lupus erythematosus, and psoriasis .
Cat. No.: HY-P990812
Target:
Research Areas:
Cat. No.: HY-19299
CAS No.: 245329-99-1
Research Areas:
Cardiovascular Disease Inflammation/Immunology Endocrinology
CI-1018 is an orally active selective PDE-4 inhibitor, with IC50 values of 1.1 μM, 35.8 μM, and 73.4 μM against hPDE-4, canine PDE-4, and guinea pig PDE-4, respectively. CI-1018 induces iNOS expression and Apoptosis. CI-1018 induces vascular injury, medial necrosis, hemorrhage, edema, thymic atrophy, ketonuria, and weight loss. CI-1018 can be used in research related to asthma, vasculitis, and mesenteric vasculitis/arteriopathy .
Cat. No.: HY-185008
CAS No.: 1580464-93-2
Target:
Research Areas:
CPP11G (Compound 11g) is a highly selective NADPH oxidase 2 (Nox2) inhibitor (IC50=20 μM). CPP11G is promising for research of inflammatory diseases (e.g., vasculitis, atherosclerosis) and Nox2-overactivated pathologies (e.g., ischemia-reperfusion injury) .
Cat. No.: HY-118854
CAS No.: 36981-91-6
Target:
Research Areas:
Fepradinol is an orally active nonsteroidal anti-inflammatory agent. Fepradinol inhibits the increase in vascular permeability induced by histamine, 5-hydroxytryptamine, and bradykinin, reduces exudate volume, prevents leukocyte migration, and suppresses acute inflammation models. Fepradinol also induces thrombotic vasculopathy with epidermal necrosis, without leukocytoclastic vasculitis; triggers occlusive contact dermatitis presenting as purpuric papulonecrotic lesions, and causes strongly positive patch test reactions. Fepradinol can be used in research related to occlusive contact dermatitis and acute inflammation .
Cat. No.: HY-118854B
CAS No.: 67704-50-1
Target:
Research Areas:
Fepradinol hydrochloride is an orally active nonsteroidal anti-inflammatory agent. Fepradinol hydrochloride inhibits the increase in vascular permeability induced by histamine, 5-hydroxytryptamine, and bradykinin, reduces exudate volume, prevents leukocyte migration, and suppresses acute inflammation models. Fepradinol hydrochloride also induces thrombotic vasculopathy with epidermal necrosis, without leukocytoclastic vasculitis; triggers occlusive contact dermatitis presenting as purpuric papulonecrotic lesions, and causes strongly positive patch test reactions. Fepradinol hydrochloride can be used in research related to occlusive contact dermatitis and acute inflammation .
Cat. No.: HY-180706
CAS No.: 99590-80-4
Target:
Cat. No.: HY-P992023
Target:
Research Areas:
Cat. No.: HY-118854A
CAS No.: 1185076-47-4
Target:
Research Areas:
Fepradinol oxalate is an orally active nonsteroidal anti-inflammatory agent. Fepradinol oxalate inhibits the increase in vascular permeability induced by histamine, 5-hydroxytryptamine, and bradykinin, reduces exudate volume, prevents leukocyte migration, and suppresses acute inflammation models. Fepradinol oxalate also induces thrombotic vasculopathy with epidermal necrosis, without leukocytoclastic vasculitis; triggers occlusive contact dermatitis presenting as purpuric papulonecrotic lesions, and causes strongly positive patch test reactions. Fepradinol oxalate can be used in research related to occlusive contact dermatitis and acute inflammation .
- 1
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
