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12 Results for "

vasodilatation

" in MedChemExpress (MCE) Product Catalog:

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Trihexyphenidyl hydrochloride

3 Cited Publications

Cat. No.: HY-B1277

CAS No.: 52-49-3

Target:

mAChR Cholinesterase (ChE)

Research Areas:

Neurological Disease

Trihexyphenidyl hydrochloride is a selective and orally active M₁ muscarinic receptor antagonist with an IC₅₀ of 3.7 nM for rat cerebral cortex M1 muscarinic receptors. Trihexyphenidyl hydrochloride modulates cholinergic activity, countering acetylcholine supersensitivity in neural pathways. Trihexyphenidyl hydrochloride improves movement disorder, inhibits McN-A-343 (HY-107648)-induced pressor responses, vagally-induced bradycardia and vasodilatation. Trihexyphenidyl hydrochloride can be used for the research of Parkinson's disease. .

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Treprostinil diethanolamine

3 Cited Publications

Cat. No.: HY-B0813

CAS No.: 830354-48-8

Synonyms: UT-15C

Target:

Prostaglandin Receptor

Research Areas:

Endocrinology

Treprostinil (UT-15C) diethanolamine is a potent EP2, DP1 and IP agonist with K_i values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FP, respectively. Treprostinil (UT-15C) diethanolamine increases upregulation of cAMP toward maintaining homeostasis within the vasculature. Treprostinil (UT-15C) diethanolamine can result in vasodilatation of human pulmonary arteries .

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Dracorhodin

2 Cited Publications

Cat. No.: HY-N4081

CAS No.: 643-56-1

Category:

Cardiovascular Disease Anthocyans Flavonoids Plants Other Families Extract Disease Research Fields

Target:

Others

Dracorhodin, the main component in sanguis draconis, is a flavylium compound belonging to the anthocyanin family. Dracorhodin can induce vasodilatation .

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Enoximone

Cat. No.: HY-B1639

CAS No.: 77671-31-9

Target:

Phosphodiesterase (PDE)

Research Areas:

Cardiovascular Disease Inflammation/Immunology

Enoximone is an inotropic vasodilating agent and a selective and orally active phosphodiesterase III (PDE3) inhibitor with an IC₅₀ of 5.9 μM. Enoximone induces vasodilatation and increases intracellular levels of cAMP by inhibiting cGMP-inhibited PDE. Enoximone also exhibits PDE4 inhibitory effect with an IC₅₀ of 21.1 μM for myocardial PDE4A. Enoximone has the potential for congestive heart failure research and has bronchodilatory, antiasthma and anti-inflammatory effects .

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