12 Results for "

weakness

" in MedChemExpress (MCE) Product Catalog:
Products (12)

12 Results for "weakness" in MCE Product Catalog:

5
GSK-2881078
GSK-2881078
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5 Cited Publications
Cat. No.: HY-100186
CAS No.: 1539314-06-1
Purity:  99.74%
Target:  

Androgen Receptor

Research Areas:  

Cardiovascular Disease Others Metabolic Disease Inflammation/Immunology Endocrinology Cancer

GSK-2881078 is an orally active and nonsteroidal selective androgen receptor modulator (SARM) which act as partial AR agonists in androgenic tissues while mainly as complete AR agonists in synthetic metabolic tissues,induces AR-mediated transcriptional activation in PC3(AR)2 cells (EC50 = 3.99 nM) and the effect can be inhibited by the non-steroidal AR antagonist Bicalutamide. GSK-2881078 can be used in research of muscle weakness and cachexia associated with both chronic and acute illness .
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Bimagrumab (WT IgG1)
Bimagrumab (WT IgG1)
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3 Cited Publications
Cat. No.: HY-P99355
CAS No.: 1356922-05-8
Synonyms: Anti-ACVR2B Reference Antibody (WT IgG1); BYM338 (WT IgG1)
Target:  

TGF-β Receptor

Research Areas:  

Metabolic Disease Inflammation/Immunology

Bimagrumab (Anti-ACVR2B Reference Antibody) (WT IgG1) is a human monoclonal antibody that retains a native wild-type Fc region and is capable of blocking the activin type II receptor (ActRII). Bimagrumab (WT IgG1) can be used in research concerning pathological muscle loss and weakness. .
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Carboxyatractyloside tripotassium
Carboxyatractyloside tripotassium
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2 Cited Publications
Cat. No.: HY-N1502
CAS No.: 77228-71-8
Synonyms: Gummiferin tripotassium
Category:  

Terpenoids Diterpenoids Plants Other Families Extract Disease Research Fields Cancer

Target:  

Mitochondrial Metabolism Reactive Oxygen Species (ROS) Calcium Channel

Carboxyatractyloside tripotassium is a diterpenoid. Carboxyatractyloside tripotassium can be isolated from plants of the genus Xanthium. Carboxyatractyloside tripotassium is an ADP/ATP carrier inhibitor, inhibiting mitochondrial ADP/ATP transport. Carboxyatractyloside tripotassium promotes ROS production, induces Ca 2+ release, and leads to mitochondrial dysfunction. Carboxyatractyloside tripotassium induces lethargy, weakness, and epileptic seizures in rats .
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Carboxyatractyloside dipotassium
Carboxyatractyloside dipotassium
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2 Cited Publications
Cat. No.: HY-N2522
CAS No.: 33286-30-5
Synonyms: Gummiferin dipotassium
Category:  

Terpenoids Other Diseases Diterpenoids Plants Other Families Extract Disease Research Fields

Target:  

Mitochondrial Metabolism Calcium Channel Reactive Oxygen Species (ROS)

Carboxyatractyloside dipotassium is a diterpenoid. Carboxyatractyloside dipotassium can be isolated from plants of the genus Xanthium. Carboxyatractyloside dipotassium is an ADP/ATP carrier inhibitor, inhibiting mitochondrial ADP/ATP transport. Carboxyatractyloside dipotassium promotes ROS production, induces Ca 2+ release, and leads to mitochondrial dysfunction. Carboxyatractyloside dipotassium induces lethargy, weakness, and epileptic seizures in rats .
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Triethyl citrate
Triethyl citrate
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Cat. No.: HY-W011602
CAS No.: 77-93-0
Target:  

Biochemical Assay Reagents

Research Areas:  

Neurological Disease

Triethyl citrate is an orally active citrate compound. Triethyl citrate induces acute toxic effects, including weakness, depression, ataxia, hyperexcitability, restlessness, dripping urine, and irregular, labored breathing. Triethyl citrate can be used in research on plasticizers for food packaging materials .
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Ignaseclant
Ignaseclant
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Cat. No.: HY-158183
CAS No.: 2354321-33-6
Purity:  99.60%
Synonyms: NMD670
Target:  

Chloride Channel

Research Areas:  

Neurological Disease

NMD670 is an orally active inhibitor of skeletal muscle specific chloride channel ClC-1 with an EC50 of 1.6 μM. NMD670 enhances neuromuscular transmission and improves muscle contraction and strength. NMD670 can be used in the study of muscle weakness and muscle fatigue .
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Triethyl citrate (Standard)
Triethyl citrate (Standard)
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Cat. No.: HY-W011602R
CAS No.: 77-93-0
Target:  

Reference Standards Biochemical Assay Reagents

Research Areas:  

Neurological Disease

Triethyl citrate (Standard) is the analytical standard of Triethyl citrate (HY-W011602). This product is intended for research and analytical applications. Triethyl citrate is an orally active citrate compound. Triethyl citrate induces acute toxic effects, including weakness, depression, ataxia, hyperexcitability, restlessness, dripping urine, and irregular, labored breathing. Triethyl citrate can be used in research on plasticizers for food packaging materials .
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Hemicholinium chloride
Hemicholinium chloride
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Cat. No.: HY-114081A
CAS No.: 18997-39-2
Synonyms: HC-3 chloride
Target:  

Choline Kinase

Research Areas:  

Neurological Disease

Hemicholinium chloride (HC-3) is a choline kinase (ChoK) inhibitor. Hemicholinium chloride Hemicholinium chloride induces ataxia and muscular weakness .
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Magnocurarine
Magnocurarine
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Cat. No.: HY-N6609
CAS No.: 6801-40-7
Category:  

Alkaloids Other Diseases Menispermaceae Extract Phenols Polyphenols Plants 500 - Internal Server Error | MedChemExpress

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