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Cat. No.: HY-187959

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SLC6A19-IN-6

SLC6A19-IN-6 is a B0AT1 (SLC6A19) inhibitor. SLC6A19-IN-6 inhibits sodium-dependent neutral amino acid transport. SLC6A19-IN-6 can be used for research on non-alcoholic steatohepatitis.

For research use only. We do not sell to patients.

CAS No.: 851269-95-9
Formula: C₁₃H₁₈ClNO₂
Molecular Weight:255.74

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

SLC6A19-IN-6 Chemical Structure

CAS No.: 851269-95-9

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

SLC6A19-IN-6 is a B0AT1 (SLC6A19) inhibitor. SLC6A19-IN-6 inhibits sodium-dependent neutral amino acid transport. SLC6A19-IN-6 can be used for research on non-alcoholic steatohepatitis^[1].

In Vitro

SLC6A19-IN-6 (Compound E4) (10 mM; 30 min) inhibits human B⁰AT1 in CHO-BC cells with an IC₅₀ of 13.7 µM in the FLIPR membrane potential assay, and acts primarily in a competitive manner^[1].
SLC6A19-IN-6 (6 min) inhibits human B⁰AT1 in CHO-BC cells with an IC₅₀ of 7.7 µM in a radioactive leucine/isoleucine flux assay^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 851269-95-9
Molecular Weight 255.74
Formula C₁₃H₁₈ClNO₂
SMILES

O=C(COC1=C(C)C=C(Cl)C=C1C)NC(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Yadav A, et al. Novel Chemical Scaffolds to Inhibit the Neutral Amino Acid Transporter BAT1 (SLC6A19), a Potential Target to Treat Metabolic Diseases. Frontiers in pharmacology. 2020;11:140. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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