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Cat. No.: HY-106197

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T-0902611

T-0902611 is an inhibitor targeting the human cytomegalovirus HCMV helicase‑primase complex. T-0902611 covalently modifies its target components, thereby disrupting complex function and inhibiting HCMV DNA replication. T-0902611 can be used in studies related to human cytomegalovirus infection.

For research use only. We do not sell to patients.

CAS No.: 350595-60-7
Formula: C₁₃H₁₆N₆O₃
Molecular Weight:304.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

T-0902611 Chemical Structure

CAS No.: 350595-60-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

All DNA/RNA Synthesis Isoforms :

In Vitro

Viral Infection

T-0902611 is a specific HCMV inhibitor that exerts anti-HCMV activity 30-fold stronger than that of Ganciclovir (HY-13637) in vitro via covalent modification of the primase component of the HCMV helicase/primase complex^[1]^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 350595-60-7
Molecular Weight 304.30
Formula C₁₃H₁₆N₆O₃
SMILES

CC1=C(C(N2C=CN=C2)=NC(N3[C@H](COCC3)C)=N1)[N+]([O-])=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Eizuru Y. Development of New Antivirals for Herpesviruses. Antiviral Chemistry and Chemotherapy, 2003,14:299‑308.

[2]. Coen DM, et al. Antiherpesvirus drugs: a promising spectrum of new drugs and drug targets. Nature reviews. Drug discovery. 2003 Apr;2(4):278-88. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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