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Cat. No.: HY-N13744

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Tetrahydrohonokiol

Tetrahydrohonokiol is a hydrogenated biphenyl neolignan derived from Honokiol (HY-N0003) through hydrogenation reduction. Tetrahydrohonokiol possesses potential antitumor activity. Tetrahydrohonokiol can be used for cancer research.

For research use only. We do not sell to patients.

CAS No.: 35406-31-6
Formula: C₁₈H₂₂O₂
Molecular Weight:270.37

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tetrahydrohonokiol Chemical Structure

CAS No.: 35406-31-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

In Vitro

Anti-cancer

Tetrahydrohonokiol (10 μM; 72 h) exhibits no significant cytotoxic activity against CCRF-CEM leukemia, U251 glioblastoma, or HCT-116 colon cancer cells^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Proliferation Assay^[2]

Cell Line:

CCRF-CEM leukemia cells, U251 glioblastoma cells, HCT-116 colon cancer cells
Concentration:

10 μM
Incubation Time:

72 h
Result:

Did not show a significant cytotoxic effect against CCRF-CEM leukemia cells, U251 glioblastoma cells, or HCT-116 colon cancer cells at 10 μM.

Related Protocols :

Subcutaneous Cell-Line-Derived Xenograft

Chemical Information

CAS No. 35406-31-6
Molecular Weight 270.37
Formula C₁₈H₂₂O₂
SMILES

OC1=CC=C(C=C1C=2C=CC(O)=C(C2)CCC)CCC
Structure Classification
- Phenols
- Polyphenols
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Fujita, et al. Honokiol, a New Phenolic Compound isolated from the Bark of Magnolia obovata THUNB. Chemical & Pharmaceutical Bulletin, vol. 20, no. 1, 1972, pp. 212–213.

[2]. Bernaskova M, et al. Synthesis of tetrahydrohonokiol derivates and their evaluation for cytotoxic activity against CCRF-CEM leukemia, U251 glioblastoma and HCT-116 colon cancer cells. Molecules (Basel, Switzerland). 2014 Jan 20;19(1):1223-37.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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