Thalidomide 5-pyrrolidine-CHO
Based on 1 Customer Validation
Thalidomide 5-pyrrolidine-CHO is a conjugate of E3 ubiquitin ligase ligand + Linker, used for the synthesis of NRX-0492 (HY-153357).
For research use only. We do not sell to patients.
- Purity : 99.73%
- CAS No.: 2416132-74-4
- Formula: C18H17N3O5
- Molecular Weight:355.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All E3 Ligase Ligand-Linker Conjugates Isoforms
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Biological Activity
Description
Chemical Information
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CAS No. 2416132-74-4
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Appearance Solid
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Molecular Weight 355.34
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Formula C18H17N3O5
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Color Light yellow to yellow
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SMILES
O=C[C@H]1CN(C2=CC3=C(C(N(C(CC4)C(NC4=O)=O)C3=O)=O)C=C2)CC1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (140.71 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8142 mL | 14.0710 mL | 28.1421 mL | 70.3552 mL |
| 5 mM | 0.5628 mL | 2.8142 mL | 5.6284 mL | 14.0710 mL | |
| 10 mM | 0.2814 mL | 1.4071 mL | 2.8142 mL | 7.0355 mL | |
| 15 mM | 0.1876 mL | 0.9381 mL | 1.8761 mL | 4.6903 mL | |
| 20 mM | 0.1407 mL | 0.7036 mL | 1.4071 mL | 3.5178 mL | |
| 25 mM | 0.1126 mL | 0.5628 mL | 1.1257 mL | 2.8142 mL | |
| 30 mM | 0.0938 mL | 0.4690 mL | 0.9381 mL | 2.3452 mL | |
| 40 mM | 0.0704 mL | 0.3518 mL | 0.7036 mL | 1.7589 mL | |
| 50 mM | 0.0563 mL | 0.2814 mL | 0.5628 mL | 1.4071 mL | |
| 60 mM | 0.0469 mL | 0.2345 mL | 0.4690 mL | 1.1726 mL | |
| 80 mM | 0.0352 mL | 0.1759 mL | 0.3518 mL | 0.8794 mL | |
| 100 mM | 0.0281 mL | 0.1407 mL | 0.2814 mL | 0.7036 mL |
Thalidomide 5-pyrrolidine-CHO Related Classifications
HY-49372A Related Classifications
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