TMEM16A modulator-1
Based on 1 Customer Validation
TMEM16A modulator-1 is a calcium-activated chloride channel (CaCC) and TMEM16A modulator that enhances the activity of the calcium-activated chloride channel TMEM16A. TMEM16A modulator-1 can be used in the research of TMEM16A-related diseases, such as studies of respiratory system diseases.
For research use only. We do not sell to patients.
- CAS No.: 2367645-32-5
- Formula: C19H18ClN3O3
- Molecular Weight:371.82
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
TMEM16A |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2367645-32-5
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Appearance Solid
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Molecular Weight 371.82
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Formula C19H18ClN3O3
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SMILES
O=C(C1=NC=CC(NC(CC2=CC(Cl)=CC=C2O)=O)=C1)NC(C)(C)C#C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (268.95 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6895 mL | 13.4474 mL | 26.8947 mL | 67.2368 mL |
| 5 mM | 0.5379 mL | 2.6895 mL | 5.3789 mL | 13.4474 mL | |
| 10 mM | 0.2689 mL | 1.3447 mL | 2.6895 mL | 6.7237 mL | |
| 15 mM | 0.1793 mL | 0.8965 mL | 1.7930 mL | 4.4825 mL | |
| 20 mM | 0.1345 mL | 0.6724 mL | 1.3447 mL | 3.3618 mL | |
| 25 mM | 0.1076 mL | 0.5379 mL | 1.0758 mL | 2.6895 mL | |
| 30 mM | 0.0896 mL | 0.4482 mL | 0.8965 mL | 2.2412 mL | |
| 40 mM | 0.0672 mL | 0.3362 mL | 0.6724 mL | 1.6809 mL | |
| 50 mM | 0.0538 mL | 0.2689 mL | 0.5379 mL | 1.3447 mL | |
| 60 mM | 0.0448 mL | 0.2241 mL | 0.4482 mL | 1.1206 mL | |
| 80 mM | 0.0336 mL | 0.1681 mL | 0.3362 mL | 0.8405 mL | |
| 100 mM | 0.0269 mL | 0.1345 mL | 0.2689 mL | 0.6724 mL |
TMEM16A modulator-1 Related Classifications
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