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Cat. No.: HY-E70347

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Tn5 Transposase

Name: Tn5 Transposase
Brand: MedChemExpress
SKU: HY-E70347
Price: 1980.00 USD
Availability: InStock
Rating: 5 (1 reviews)

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Tn5 Transposase is a cut-and-paste type transposase that catalyzes DNA transposition.

For research use only. We do not sell to patients.

CAS No.: 308064-67-7

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Tn5 Transposase Chemical Structure

CAS No.: 308064-67-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
- Enzyme Activity
- Unit Definition
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Tn5 Transposase is a cut-and-paste type transposase that catalyzes DNA transposition^[1]^[2]^[3].

All Endogenous Metabolite Isoforms :

In Vitro

The single-chain dimer of Tn5 Transposase exhibits higher activity than the wild-type monomer in prokaryotes^[1].
Tn5 Transposase is a core component of the nanoCUT&Tag workflow, enabling low-input epigenomic profiling of histone modifications and transcription factors in FANS-enriched brain nuclei^[2].
Tn5 Transposase efficiently fragments high-molecular-weight DNA into 400-500 bp fragments in vitro^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Enzyme Activity

1000 U/mL

Unit Definition

One unit is defined as the amount of enzyme that cleaves 1 μg DNA fragment containing recognition sequence in 1 hourat 37°C

Chemical Information

CAS No. 308064-67-7
Appearance Liquid
Color Colorless to light yellow
SMILES

[Tn5 Transposase]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Blundell-Hunter G. Manipulation of the Tn5 transpososome assembly pathway and its effect on reaction dynamics.

[2]. Ziegler KC, et al. Brain cell type nuclei enrichment without fixative for nanoCUT&Tag and other omics approaches. bioRxiv. 2026 Apr 6:2026-03.

[3]. Picelli S, et al. Tn5 transposase and tagmentation procedures for massively scaled sequencing projects. Genome research. 2014 Dec;24(12):2033-40.

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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Minimum order quantity

100 mg

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