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Cat. No.: HY-B0458B

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trans-Cefprozil

trans-Cefprozil is a trans-isomer of Cefprozil (HY-B0458A). Cefprozil is a cephalosporin Antibiotic. trans-Cefprozil exhibits antibacterial activity. The antibacterial activity of trans-Cefprozil against Gram-positive bacteria is similar to that of cis-Cefprozil, but its activity against Gram-negative bacteria is lower than that of cis-Cefprozil. trans-Cefprozil can be used for research on Staphylococcus aureus and Escherichia coli infections.

For research use only. We do not sell to patients.

CAS No.: 92676-86-3
Formula: C₁₈H₁₉N₃O₅S
Molecular Weight:389.43

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

trans-Cefprozil Chemical Structure

CAS No.: 92676-86-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

All Antibiotic Isoforms :

In Vitro

Bacterial Infection

trans-Cefprozil exhibits antibacterial activity against Gram-positive bacteria similar to that of cis-Cefprozil, but its activity against Gram-negative bacteria is six-fold lower than that of cis-Cefprozil^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 92676-86-3
Molecular Weight 389.43
Formula C₁₈H₁₉N₃O₅S
SMILES

C(O)(=O)C=1N2[C@@]([C@H](NC([C@H](N)C3=CC=C(O)C=C3)=O)C2=O)(SCC1/C=C/C)[H]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Jang JH, et al. Population Pharmacokinetics of Cis-, Trans-, and Total Cefprozil in Healthy Male Koreans. Pharmaceutics. 2019 Oct 14;11(10):531.

[2]. Shengxi F, et al. Enzymatic synthesis and in vitro antibacterial activity of trans-cefprozil[J]. 2010.

[3]. He G, et al. Development and Validation of an HPLC-MS/MS Method for Rapid Simultaneous Determination of Cefprozil Diastereomers in Human Plasma. International journal of analytical chemistry. 2018;2018:6959761.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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