Trastuzumab rezetecan
Based on 1 publication(s) in Google Scholar
Trastuzumab rezetecan (SHR-A1811) is a HER2-targeting antibody-drug conjugate (ADC). Trastuzumab rezetecan is composed of a humanized anti-HER2 antibody (HY-P9907), a cleavable linker MC-Gly-Gly-Phe-Gly (HY-44246), and a topoisomerase I inhibitor payload Rezetecán (HY-147408). Trastuzumab rezetecan can be used for research in HER2-positive breast cancer.
For research use only. We do not sell to patients.
- Purity : 98.01%
- CAS No.: 2924909-11-3
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Storage:
-80°C, protect from light
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Trastuzumab rezetecan
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Biological Activity
Description
IC50 & Target
[1]|
HER2 |
In Vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Clinical Trial
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 2924909-11-3
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Appearance Liquid
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Color Colorless to light yellow
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SMILES
[Trastuzumab rezetecan]
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Synonyms
SHR-A1811
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Shipping
Shipping with dry ice.
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Storage
-80°C, protect from light
Publications (1)
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Journal Impact Factor
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Most Recent
Purity & Documentation
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Data Sheet (267 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Trastuzumab rezetecan Related Classifications
HY-164762 Related Classifications
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