TTBK1/2-IN-1
Based on 1 Customer Validation
TTBK1/2-IN-1 (compound 3) is a potent Tau tubulin kinase 1 (TTBK1) and TTBK2 inhibitor with IC50s of 816 nM and 384 nM, respectively.
For research use only. We do not sell to patients.
- Purity : 98.16%
- CAS No.: 2342571-09-7
- Formula: C17H16N4O
- Molecular Weight:292.34
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
Chemical Information
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CAS No. 2342571-09-7
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Appearance Solid
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Molecular Weight 292.34
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Formula C17H16N4O
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Color Light yellow to yellow
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SMILES
NC1=NC=CC(C2=CNC3=C2C=C(C#CC(C)(O)C)C=C3)=N1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (342.07 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4207 mL | 17.1034 mL | 34.2067 mL | 85.5169 mL |
| 5 mM | 0.6841 mL | 3.4207 mL | 6.8413 mL | 17.1034 mL | |
| 10 mM | 0.3421 mL | 1.7103 mL | 3.4207 mL | 8.5517 mL | |
| 15 mM | 0.2280 mL | 1.1402 mL | 2.2804 mL | 5.7011 mL | |
| 20 mM | 0.1710 mL | 0.8552 mL | 1.7103 mL | 4.2758 mL | |
| 25 mM | 0.1368 mL | 0.6841 mL | 1.3683 mL | 3.4207 mL | |
| 30 mM | 0.1140 mL | 0.5701 mL | 1.1402 mL | 2.8506 mL | |
| 40 mM | 0.0855 mL | 0.4276 mL | 0.8552 mL | 2.1379 mL | |
| 50 mM | 0.0684 mL | 0.3421 mL | 0.6841 mL | 1.7103 mL | |
| 60 mM | 0.0570 mL | 0.2851 mL | 0.5701 mL | 1.4253 mL | |
| 80 mM | 0.0428 mL | 0.2138 mL | 0.4276 mL | 1.0690 mL | |
| 100 mM | 0.0342 mL | 0.1710 mL | 0.3421 mL | 0.8552 mL |