UNC10112785
UNC10112785 is a serine/threonine kinase inhibitor with a human GSK-3β IC50 of 0.031 μM, human CDK-2 IC50 of 0.016 μM, and human CDK-4 IC50 of 1.99 μM. UNC10112785 can be used for the research of type 2 diabetes.
For research use only. We do not sell to patients.
- CAS No.: 748142-06-5
- Formula: C19H18N6
- Molecular Weight:330.40
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
[1]|
CDK2 0.016 μM (IC50) |
GSK-3 0.031 μM (IC50) |
CDK4 1.99 μM (IC50) |
In Vitro
UNC10112785 (compound 22) (40 min) inhibits human GSK-3β (IC50 = 0.031 μM), CDK-2 (IC50 = 0.016 μM) and CDK-4 (IC50 = 1.99 μM) in in vitro enzymatic activity assays[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 748142-06-5
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Molecular Weight 330.40
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Formula C19H18N6
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SMILES
N1=CC=C(N=C1NC2=CC=C(C=C2)C(C)C)C=3C=NN4N=CC=CC34
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)