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Cat. No.: HY-186374

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WDR5-IN-10

WDR5-IN-10 is a WDR5 inhibitor. WDR5-IN-10 inhibits WDR5 with a K_i < 0.02 nM and inhibits WDR5-mediated protein-protein interactions. WDR5-IN-10 can be used for cancer-related research.

For research use only. We do not sell to patients.

CAS No.: 2642333-22-8
Formula: C₃₁H₂₈F₃N₇O₂
Molecular Weight:587.59

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

WDR5-IN-10 Chemical Structure

CAS No.: 2642333-22-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

WDR5-IN-10 is a WDR5 inhibitor. WDR5-IN-10 inhibits WDR5 with a K_i < 0.02 nM and inhibits WDR5-mediated protein-protein interactions. WDR5-IN-10 can be used for cancer-related research^[1].

In Vitro

WDR5-IN-10 (Example 93) has an inhibition K_i < 0.02 nM against WDR5 in the TR-FRET binding assay and inhibits WDR5-mediated protein-protein interactions^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2642333-22-8
Molecular Weight 587.59
Formula C₃₁H₂₈F₃N₇O₂
SMILES

O=C(C1=CC(CC)=CC2=C(N3C(C4=CC(CN5C=NC=C5)=CC(C6=CN(C)N=C6C(F)(F)F)=C4CC3)=O)C=CN=C21)NC
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Lee T, et al. Wdr5 inhibitors and modulators. WO2021092525A1, 2021.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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