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Cat. No.: HY-N21819

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Wyerone

Wyerone is a furan-acetylene phytoalexin that exhibits antifungal activity and selective toxicity against Gram-positive bacteria. Wyerone is abundantly biosynthesized and accumulated in broad bean tissues following infection by Botrytis, and it inhibits the growth of Gram-positive bacteria. Wyerone is applicable to studies related to plant infections.

For research use only. We do not sell to patients.

CAS No.: 20079-30-5
Formula: C₁₅H₁₄O₄
Molecular Weight:258.27

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Wyerone Chemical Structure

CAS No.: 20079-30-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
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- In Vitro
Chemical Information
Purity & Documentation
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Biological Activity

Description

All Endogenous Metabolite Isoforms :

In Vitro

Bacterial InfectionOthers

Bacterial Infection

Wyerone exhibits selective antibacterial activity: it inhibits all tested Gram-positive bacterial strains while showing no activity against any of the tested Gram-negative strains. Furthermore, when Wyerone is applied to assay filter discs using different solvents such as acetone, diethyl ether, or methanol, there is no significant difference in the measured sizes of the inhibition zones against Gram-positive bacteria^[1].
Wyerone produces clear inhibition zones against all 5 tested Gram-positive bacteria, and this effect occurs at concentrations no higher than 4 μg per disc. Overall, the area of the inhibition zones shows an increasing trend as the concentration rises from 2 μg per disc to 10 μg per disc^[1].
Wyerone (up to 30 μg per disk; 24 h) induces concentration-dependent increases in the area of inhibition zones in Bacillus megaterium cultures, with the maximum effective concentration reaching 30 μg per disk; no additional growth inhibitory effect is observed above this concentration^[1].

Others

Wyerone (4 days post-infection): When broad bean leaves are infected by Botrytis fabae, the biosynthesis of wyerone is strongly stimulated, reaching a peak of 45 μg/g on day 4 post-infection^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS No. 20079-30-5
Molecular Weight 258.27
Formula C₁₅H₁₄O₄
SMILES

CC/C=C\C#CC(C1=CC=C(/C=C/C(OC)=O)O1)=O
Structure Classification
- Others
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Gnanamanickam S S. Selective toxicity of wyerone and other phytoalexins to gram‑positive bacteria. Phytochemistry. 1981;20 (5):997‑1000.

[2]. Fawcett C H, et al. Wyerone increase in leaves of broad bean (Vicia faba L.) after infection by Botrytis fabae. Physiological Plant Pathology. 1971;1 (2):163‑166.

[3]. Cain R O, Porter A E A. Biosynthesis of the phytoalexin wyerone in Vicia faba. Phytochemistry. 1979;18 (2):322‑323.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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