Xenin-8 acetate
Based on 1 Customer Validation
Xenin-8 acetate is the C-terminal octapeptide fragment of xenin, which belongs to the xenopsin family of peptides. Xenin-8 acetate stimulates basal insulin secretion, dose-dependently enhances glucose (EC50 = 0.16 nM) and arginine-induced insulin release, and enhances arginine- and Carbamoylcholine chloride (HY-B1208)-induced glucagon secretion. Xenin-8 acetate antagonizes the inhibition of glucagon release by elevated glucose. Xenin-8 acetate can be used in research on type 2 diabetes and obesity-related glucose metabolic disorders.
For research use only. We do not sell to patients.
- Purity : 99.46%
- Formula: C51H79N15O9·xC2H4O2
- Molecular Weight:1046.27 (free base)
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Storage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Xenin-8 acetate is able to antagonize the inhibition of glucagon release caused by elevated glucose concentrations[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Solid
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Molecular Weight 1046.27 (free base)
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Formula C51H79N15O9·xC2H4O2
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Color White to off-white
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SMILES
O=C(N1[C@@H](CCC1)C(N[C@@H](CCCCN)C(N[C@@H](CCCNC(N)=N)C(N2[C@@H](CCC2)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC5=CNC=N5)N.CC(O)=O.[x]
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Sequence
His-Pro-Lys-Arg-Pro-Trp-Ile-Leu
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Sequence Shortening
HPKRPWIL
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Purity & Documentation
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Data Sheet (296 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Xenin-8 acetate Related Classifications
HY-P1257B Related Classifications
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