XY-06-005
XY-06-005 is a modified selective inhibitor of BET bromodomain that binds to BRD4 BD1 L94V, BRD4 BD2 L387V and BRD2 BD2 L383V. XY-06-005 serves as a Ligand for Target Protein for PROTAC for studies related to PROTAC synthesis, such as acting as the target protein ligand structure of XY-06-007 (HY-145226).
For research use only. We do not sell to patients.
- CAS No.: 1642783-78-5
- Formula: C22H21ClN4O3
- Molecular Weight:424.88
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
BRD4 BD1 |
BRD4 BD2 |
BRD4 BD1L94V |
In Vitro
XY-06-005 can serve as the target protein ligand structure of XY-06-007 (HY-145226). XY-06-007 is a potent and selective B&H-PROTAC BRD4 BD1 L94V degrader with a DC50 of 10 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1642783-78-5
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Molecular Weight 424.88
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Formula C22H21ClN4O3
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SMILES
ClC1=CC=C(C2=N[C@H](C3=NN=C(N3C4=C2C=C(C=C4)OC)C)[C@H](C(OC)=O)C)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
XY-06-005 Related Classifications
HY-184949 Related Classifications
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