YH-685
YH-685 is a cytochrome bd oxidase (Cyt-bd) inhibitor. YH-685 enhances the inhibitory effect of Cyt-bcc inhibitors on planktonic and intracellular Mycobacterium tuberculosis by targeting the terminal oxidase of the mycobacterial electron transport chain. YH-685 can be used for research on tuberculosis.
For research use only. We do not sell to patients.
- CAS No.: 3037358-52-1
- Formula: C18H12F5NO3
- Molecular Weight:385.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | IC50 |
61.7 μM
|
Cytotoxicity against human HepG2 cells.
Cytotoxicity against human HepG2 cells.
|
acsmedchemlett.6c00310 |
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3037358-52-1
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Molecular Weight 385.28
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Formula C18H12F5NO3
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SMILES
O=C1C(CC2=CC=C(OC(F)(F)F)C=C2)=C(C)N(O)C3=C1C=C(F)C(F)=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)