(Z)-SMI 6860766
Based on 1 Customer Validation
(Z)-SMI 6860766 is an isomer of SMI 6860766 (HY-125025). SMI 6860766 is a small-molecule inhibitor of the CD40-TRAF6 interaction that improves glucose tolerance, reduces immune cell accumulation in adipose tissue, and decreases adipose tissue (AT) inflammation.
For research use only. We do not sell to patients.
- Formula: C15H11BrClNO
- Molecular Weight:336.61
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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Appearance Solid
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Molecular Weight 336.61
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Formula C15H11BrClNO
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SMILES
O=C(/C=C\NC1=CC=C(C=C1Cl)Br)C2=CC=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 25 mg/mL (74.27 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9708 mL | 14.8540 mL | 29.7080 mL | 74.2699 mL |
| 5 mM | 0.5942 mL | 2.9708 mL | 5.9416 mL | 14.8540 mL | |
| 10 mM | 0.2971 mL | 1.4854 mL | 2.9708 mL | 7.4270 mL | |
| 15 mM | 0.1981 mL | 0.9903 mL | 1.9805 mL | 4.9513 mL | |
| 20 mM | 0.1485 mL | 0.7427 mL | 1.4854 mL | 3.7135 mL | |
| 25 mM | 0.1188 mL | 0.5942 mL | 1.1883 mL | 2.9708 mL | |
| 30 mM | 0.0990 mL | 0.4951 mL | 0.9903 mL | 2.4757 mL | |
| 40 mM | 0.0743 mL | 0.3713 mL | 0.7427 mL | 1.8567 mL | |
| 50 mM | 0.0594 mL | 0.2971 mL | 0.5942 mL | 1.4854 mL | |
| 60 mM | 0.0495 mL | 0.2476 mL | 0.4951 mL | 1.2378 mL |
(Z)-SMI 6860766 Related Classifications
HY-125025A Related Classifications
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