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Cat. No.: HY-113038AR

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α-Hydroxyglutaric acid disodium (Standard)

Name: α-Hydroxyglutaric acid disodium (Standard)
Brand: MedChemExpress
SKU: HY-113038AR
Price: 100.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: 2-Hydroxyglutarate disodium (Standard); 2-Hydroxyglutaric acid disodium (Standard); 2-Hydroxypentanedioic acid disodium (Standard))

α-Hydroxyglutaric acid disodium (Standard) (2-Hydroxyglutarate disodium (Standard)) is the analytical standard of α-Hydroxyglutaric acid disodium (HY-113038A). This product is intended for research and analytical applications. α-Hydroxyglutaric acid (2-Hydroxyglutarate) disodium is an α-hydroxy acid form of glutaric acid. α-Hydroxyglutaric acid disodium is a competitive inhibitor of multiple α-ketoglutarate-dependent dioxygenases, including histone demethylases and the TET family of 5-methlycytosine (5mC) hydroxylases.

For research use only. We do not sell to patients.

Purity : 0%
CAS No.: 40951-21-1
Formula: C₅H₆Na₂O₅
Molecular Weight:192.08

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

α-Hydroxyglutaric acid disodium (Standard) Chemical Structure

CAS No.: 40951-21-1

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Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 40951-21-1
Molecular Weight 192.08
Formula C₅H₆Na₂O₅
SMILES

O=C(O[Na])C(O)CCC(O[Na])=O
Synonyms

2-Hydroxyglutarate disodium (Standard); 2-Hydroxyglutaric acid disodium (Standard); 2-Hydroxypentanedioic acid disodium (Standard)
Structure Classification
- Ketones, Aldehydes, Acids
Initial Source
- Endogenous metabolite
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Wei Xu, et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. Cancer Cell. 2011 Jan 18;19(1):17-30. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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α-Hydroxyglutaric acid disodium (Standard)

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α-Hydroxyglutaric acid disodium (Standard)

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α-Hydroxyglutaric acid disodium (Standard) Related Classifications

HY-113038AR Related Classifications

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