1-Decanesulfonic acid
1-Decanesulfonic acid is an alkanesulfonate anionic surfactant that acts as a neutralizer of plasminogen activator inhibitor-1 (PAI-1). 1-Decanesulfonic acid binds to the hydrophobic region in the flexible linker domain of active PAI-1. 1-Decanesulfonic acid induces PAI-1 polymerization via a two-step neutralization mechanism.
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- CAS No.: 20283-21-0
- Formula: C10H22O3S
- Molecular Weight:222.34
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 20283-21-0
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Molecular Weight 222.34
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Formula C10H22O3S
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SMILES
O=S(=O)(O)CCCCCCCCCC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Egelund R, et al. A regulatory hydrophobic area in the flexible joint region of plasminogen activator inhibitor-1, defined with fluorescent activity-neutralizing ligands. Ligand-induced serpin polymerization. J Biol Chem. 2001 Apr 20;276(16):13077-86. [Content Brief]
[2]. Bruzzoniti MC, et al. Determination of sulfonic acids and alkylsulfates by ion chromatography in water. Talanta. 2008 May 15;75(3):734-9. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
1-Decanesulfonic acid Related Classifications
HY-187154 Related Classifications
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